482 例儿童手足口病流行病学与临床特点分析[J].pdfVIP

实  践  与  交  流 2009, 9(7): 815 816 中国循证医学杂志 ～ 482例儿童手足口病流行病学与临床特点分析 1 1 1 1 2 1,* 李茂军  张  熔  赵  娟  李运璧  刘思雨  陈昌辉 1. 四川省医学科学院 四川省人民医院儿科（成都 610072 ）； 2. 四川省医学科学院 四川省人民医院预防保健科（成都 610072 ） 摘要  目的 调查成都地区 2008 年儿童手足口病流行病学与临床特点。方法 对四川省人民医院 2008 年收 治的 482 例手足口病儿童进行回顾性调查，分析其流行病学与临床特点。结果 该 482 例手足口病患儿中，76.14% 为婴幼儿，男性多于女性，城市发病率高于乡村。每年 5 ～7 月是该病的高发季节。临床表现主要为皮疹和发热，3 例合并病毒性脑炎。结论 手足口病发病与年龄、季节有关，有效的预防措施和积极的隔离治疗至关重要。 关键词 手足口病；流行病学；临床分析 Etiology and Clinical Characteristics of 482 Children with Hand-Foot-Mouth Disease 1 1 1 1 2 1,* LI Mao-jun , ZHANG Rong , ZHAO Juan , LI Yun-bi , LIU Si-yu , CHEN Chang-hui Sichuan Academy of Medical Sciences Sichuan Provincial Peoples Hospital, Chengdu 610072, China Abstract Objective To investigate the etiological and clinical characteristics of the outbreak of hand-foot-mouth disease (HFMD) in Chengdu in 2008. Methods A retrospective analysis was conducted to investigate 482 children with hand-foot-mouth disease in Chengdu from January to December 2008 in terms of epidemiology and clinical characteristics. Results Among the 482 children, 76.14% of the cases were infants, and male children numbered more than female ones. The proportion in the urban area was higher than that in the rural area. May to July was the peak epidemic period. Skin rash and fever were major clinical manifestations. Three cases were diagnosed as viral encephalitis. Conclusion The incidence of hand-foot-mouth disease is related to age and season. Effective prevention measures and isolated treatment are critical for prevention and therapy. Key words Hand-foot-and-mouth disease;Epidemiology; Clinical analysis 手足口病（hand-foot-mouth