腮腺嗜酸细胞癌的临床病理观察.pdfVIP

10·38 · 洪良利，等 腮腺嗜酸细胞癌的临床病理观察 ?头颈肿瘤? 腮腺嗜酸细胞癌的临床病理观察 洪良利 ，秦杰升 ，黄杰雄1 2 1 Ｐｒｉｍａｒｙ ｏｎｃｏｃｙｔｉｃ ｃａｒｃｉｎｏｍａ ｏｆ ｔｈｅ ｓａｌｉｖａｒｙ ｇｌａｎｄｓ ：ｃｌｉｎｉｃａｌ ａｎｄ ｐａｔｈｏｌｏｇｉｃ ｓｔｕｄｙ ｏｆ 2 ｃａｓｅｓ 1 2 1 eongLiangli ，QinJiesheng ，euangJiexiong 1DepartmentofPathology；DepartmentofHeadandNeckSurgery，theFirstAffiliatedHospitaltoShantouUniversityMedicalCollege，2 GuangdongShantou515041，China. 【Abstract】 Objective：ToexPloretheclinicoPathologicfeatures，diagnosisanddifferentialdiagnosisofoncocytic carcinomaintheParotidgland.Methods：TwocasesofoncocyticcarcinomawererePorted.Theclinicaldata，Patholog- icalandimmunohistochemicalfeatureswerereviewedanddiscussedwiththerelevantliterature.Results：Oncocytic carcinomawasmainlyfoundasaPainless，i egular-shaPedmassorlymPhadenectasisinParotidglandregion.Itisa rareProliferationofmalignantoncocyteswithProminentnucleoliandinfiltrativequalities.SurgerywasthePrinciPle treatment，andPostoPerativeradiotheraPywasusedasadjuvanttreatment.TherewerenocomPlicationsandnosignof recu enceofthetwocaseswithfollow-uPfor6to33months.Conclusion：Oncocyticcarcinomaisanextremelyrare malignancyinheadandneck.Differentialdiagnosesincludedoncocyticadenoma，aciniccellcarcinoma，mucoePder- moidcarcinoma.RadicalresectionwithPostoPerativeradiotheraPyisthemaintreatment.ThePrognosisofoncocytic carcinomamaybeassociatedwithtumorstage，regionallymPhnodemetastasesandcomPletesurgicalexcision. 【Keywords】oncocyticcarcinoma；salivarygland；clinicalPathology ModernOncology2014，22（05）：1038-1040 【摘要】 目的：观察腮腺嗜酸细胞癌（oncocyticcarcinoma）的临床病理组织学特征、诊断与鉴别诊断，探讨其 治疗与预后。方法：对2例腮腺嗜酸性细胞癌进行临床、病理组织学形态观察，并进行随访。结果：腮腺嗜酸 细胞癌临床多表现为腮腺区无痛性、不规则肿块或颈淋巴结肿大。病理学表现为嗜酸性大细胞，异形性明 显，核仁显著和浸润性生长特征。首次手术彻底切除是嗜酸细胞癌的首选治疗方法，术后可结合放疗。2例 患者随访6-33个月，均未发现复发或转移。结论：腮腺嗜酸细胞癌是一种