颈动脉结构功能改变与冠状动脉病变关系的探讨.DOCVIP

临床医学论文-颈动脉结构功能改变与冠状动脉病变关系的探讨 ??????????????????? 作者：刘奕　黄宜杰　王璐璐　蒋树中　张毅刚　李先进　付强 【关键词】? 颈动脉 　　摘要：目的：探讨超声心动仪检测颈动脉结构及功能改变与冠状动脉病变及其严重程度之间相关关系。方法：87例住院患者，根据冠脉造影（CAG）结果分为冠脉单支病变组（A组）、多支病变组（B组），CAG阴性者作为对照组（C组）。全部病例采用超声心动仪检测双侧颈动脉内径、斑块情况、内膜―中层厚度（IMT）。结果：颈动脉结构及功能改变与年龄显著相关。冠脉狭窄组的斑块发生率、斑块面积和Cuorse积分均显著高于对照组，且多支病变组明显高于单支病变组，统计学有显著性差异。结论：颈动脉粥样硬化及严重程度对冠心病有较高的预测价值。 　　关键词:动脉粥样硬化;颈动脉;冠状动脉;超声心动仪 　　Study the Relationship Between the Change of Carotid Construction and Function and Coronary Stenosis 　　Abstract： Objective： To study the correlativity between the change of carotid construction and function detected with ultrasound cardiotachograph and the various degree of coronary stenosis. Method： Eighty-seven cases who accepted coronary angiography were divided into three groups: mono-vessel disease group(A group), multi-vessel disease group(B group) and normal vessel group(C group) ,C group was control group.? Ultrasound cardiotachograph detected the inner diameter, the intima-media thickness (IMT) and the plaque information of carotid artery in all patients. Result： The change of carotid construction and function correlated with age significantly. The incidence rate, areas and the Cuorse score of plaque in coronary stenosis group were much higher than that in control group, and multi-vessel group were obviously higher than mono-vessel group, which have statistically significant difference. Conclusion： It is valuable that through carotid artery atherosclerosis and its severity degree predict coronary artery disease. 　　Key words：Atherosclerosis；Carotid artery；Coronary；Ultrasound cardiotachograph????????????????????????????????????????????????????????????? 　　动脉粥样硬化（atherosclerosis AS）是一种全身性疾病，作为循环系统的主要动脉中的颈动脉及冠状动脉常同时受累，在此基础上的管腔狭窄或阻塞常引起缺血性心脑血管病，本文旨在通过颈动脉超声及冠脉造影结果来探讨二者的关系。 　　1 资料与方法 　　1.1 研究对象：2004年1月至10月87例临床怀疑或确诊冠心病患者，男66例，女21例，年龄59.7±15.2岁（34～83岁），其中合并高血压44例，糖尿病38例，心律失常5例。根据CAG结果分为三组：单支病变组（A组，22例，男19例、女3例，平均年龄60.3±8.9岁）；多支病变组（B组，34例，男32例、女2例，平均年龄62.5±8.7岁）；CAG阴性作为对照组（C组，31例，男26例、女5例，平均年龄5