心理干预联合舍曲林对强迫症患者生活质量的影响.docVIP

心理干预联合舍曲林对强迫症患者生活质量的影响 杨玲1 余学1 李茹2 【摘要】：目的 探讨心理干预联合舍曲林对强迫症患者生活质量的影响。方法 60例强迫症患者随机分为研究组30例和对照组30例。研究组给予心理干预联合舍曲林治疗，对照组单用舍曲林治疗，观察8周。采用Yale-Brown强迫量表和生活质量综合评定问卷（GQOLI-74）分别于治疗前和治疗后8周来进行疗效和生活质量评定。结果 和单用舍曲林相比，心理干预联合舍曲林对患者强迫症状的改善好于单用舍曲林治疗，对躯体功能、心理功能、和社会功能的改善明显优于单用舍曲林组（p0.05）。结论 心理干预联合舍曲林可以更好的改善患者的生活质量。 【关键词】 心理干预； 舍曲林； 强迫症； 生活质量 Influence of sertraline combined with psychological intervention on quality of life in patients with obsessive-compulsive disorder. Yang Ling , Yu Xue，Li Xu. Zhumadian mental hospital, Zhuma dian ,463000, P.R. China. 【Abstract】 objective To explore the influence of sertraline combined with psychological intervention on quality of life in patients with obsessive-compulsive disorder（OCD）. Methods 60 patients with OCD were randomly divided into study group(n=30) and control group(n=30). The study group were treated with psychological intervention sertraline combined with , and control group were only treated with sertraline. The effically and quality of life were measured with Yale-Brown obsessive-compulsive rating scale and general quality of life inventory –74（GQOLI-74）before and after 8 weeks treatment. Results Compared with control group, psychological intervention combined with sertraline had better efficacy in treating OCD (P0.05). Psychological intervention combined with sertraline improved physical function ,psychological function and social function significantly than sertraline group at the end of study (p0.05). Conclusions Psychological intervention combined with sertraline can better improve the quality of life in patients with OCD compared with single sertraline. 【Key words】 Psychological Intervention; Sertraline; OCD; Quality of Life 强迫症也称强迫性神经官能症，以反复持久出现强迫观念和强迫动作为主要特征，。Yale-brown 强迫量表（Y-BOCS）≥16分；排除严重躯体疾病者、妊娠及哺乳期妇女，癫痫患者。共60例，按投币法随机分为两组。 研究组给予心理干预联合舍曲林治疗，共30例，男16例，女14例；年龄16-55岁，平均（25.4±18.3）岁；病程3个月-15年，平均（3.2±4.5）年。对照组单用舍曲林治疗，共30例，其中男18例，女12例；年纪16-50岁，平均（24.9±5.7）岁；病程3个月—16年，平均（3.4±4.8）年。两组以上各项比较无显著性差异（p0.05）。