608株不动杆菌的来源分布及耐药特征分析.pdfVIP

318 Chin J Hemorh.2012;22(2) doi:10.3969/j.issn.1009-881X.2012.02.049 608株不动杆菌的来源分布及耐药特征分析 邱善敏，贾 鹏，钱雪峰 （苏州大学附属第一医院检验科，江苏苏州 215006） 摘要：目的 了解临床分离的不动杆菌对15种抗生素的耐药特征，为该类感染的药物选择提供依据。方法 收集2007年 11 月～2009年 11月临床标本中分离到的不动杆菌，用VITEK全自动微生物分析仪进行鉴定及药敏实验。结果 608株不动杆菌 中鲍曼不动杆菌538株，洛菲不动杆菌70株，药敏结果显示，鲍曼不动杆菌对亚胺培南最为敏感，耐药率27.1%；其次为头 孢哌酮/舒巴坦，耐药率为27.9%。而洛菲不动杆菌对所有药物的耐药率均较低，多数在30%以下。结论 不动杆菌是医院感 染的重要病原菌，鲍曼不动杆菌耐药率最高，部分菌株呈多重耐药，临床抗感染治疗应根据药敏试验结果选用合适抗菌药 物。 关键词：不动杆菌；药敏试验；耐药特征 中图法分类号：R446.5 文献标识码：A 文章编号：1009-881X(2012)02-0318-03 The Distribution and the Resistance Characteristics of 608 Strains of Acinetobacter QIU Shan-min,JIA Peng,QIAN Xue-feng (Department of Clinical Laboratory,the First Hospital Affi liated of Soochow University,Suzhou,Jiangsu, 215006,China) Abstract ：Objective To investigate the distribution and the resistance characteristics on 15 kinds of antibiotics of 608 strains of Acinetobacter clinical isolates in our hospital,to provide the basis for selection of anti-infectives.Methods From Nov.2007 to Nov.2009,in our hospital,isolated Acinetobacter from clinical specimens,with the VITEK Automated Microbiology Analyzer identification and susceptibility testing.Results In 608 Acinetobacter baumannii 538,70 strains of Acinetobacter Lwoffi ,drug susceptibility results showed that A.baumannii is most sensitive to imipenem,resistance was 27.1%;followed by cefoperazone/sulbactam,resistance rate was 27.9%.The Lwoffi Acinetobacter resistant to all drugs were low,most under 30%.Conclusions Acinetobacter is an important pathogen of nosocomial infection,with high resistance rate of Acinetobacter baumannii.Some strains were