中西医结合治疗对慢性荨麻疹患者血清IL-8和IL-17的影响.pdfVIP

中西医结合治疗对慢性荨麻疹患者 血清IL．8和IL一17的影响 崔存柱 【摘要】 目的探讨中西医结合对慢性荨麻疹患者血清IL一8和IL一17水平的影响。方法126例慢性 荨麻疹患者按照数字表法随机分为两组，对照组63例，观察组63例，对照组采用盐酸西替利嗪和依巴斯汀治 疗，观察组在上述治疗的基础上加用中药治疗，两组均治疗4周。治疗前后测定血清IL．8和IL．17。结果对 照组显效率为77．8％，观察组为95．2％，两组差异有统计学意义(×2=4．78，P0．05)。治疗后两组血清IL一8 和IL．17均明显降低，观察组降低更明显(t=2．92、3．06，均P0．05)。结论中西医结合治疗可以明显降低 慢性荨麻疹患者血清IL-8和IL一17。 【关键词】荨麻疹；中药；白细胞介素 Theeffectivenessof onserulllIL-8 integrativetherapy andIL-17in withchronicurticaria patients Cui of TraditionalChineseMedicine Cunzhu．DepartmentDermatology，the HospitalofHuangdaoD括trict，Qingdao， Shandong266500，China To theeffectivenessof onsenlmIL一8andIL．17in 【Abstract】Objectivestudy integrativetherapy patients withchronicurticaria．Methodstothe urticariawere withchronic Accordingdigitaltable，126patients randomly dividedintothe two control theobservation in groups，thegroup(n=63cases)and cases)．The group(n=63 patients thecontrolweretreated cetirizine and the intheobservation group through hydrochlorideebastine，whilepatients group weretreated cetirizine andebastinetraditionalchinese weretreatedfor through hydrochloride plus medicine．They 4weeks．SerumandIL一17 IL．8 weredetectedbeforeandaftertreatment．ResultsTheeffectiverateswere77．8％in controland95．2％intheobservationwitha differencebetweenthetwo group group significant 8，