四种药物治疗细菌性阴道炎的药物经济学评价.pdfVIP

四种药物治疗细菌性阴道炎的药物经济学评价 郭 宇 【摘要】 目的探讨硝呋太尔制霉素栓、乳酸菌阴道胶囊、双唑泰阴道泡腾片及聚甲酚醛栓四种药物治 疗细菌性阴道炎的成本效果，为临床合理用药提供指导。方法 随机选取分别使用硝呋太尔制霉素栓 (92例)、乳酸菌阴道胶囊(88例)、双唑泰阴道泡腾片(90例)及聚甲酚醛栓(91例)治疗的细菌性阴道炎门 诊患者361例，比较用药一个疗程的治疗效果、用药成本及不良反应，运用药物经济学成本．效果分析法评价 四种治疗方案的成本效果。结果硝呋太尔制霉素栓、乳酸菌阴道胶囊、双唑泰阴道泡腾片及聚甲酚醛栓总 有效率分别为78．26％、76．14％、83．33％、78．02％，四组总有效率差异无统计学意义(P0．05)；双唑泰阴道 泡腾片具有最小的成本-效果比(C／E，0．26)。结论从药物经济学角度来看，双唑泰阴道泡腾片是治疗细菌 性阴道炎的较佳选择。 【关键词】细菌性阴道炎；药物治疗；药物经济学 The evaluationsoffour inthetreatmentofbacterial Guo pharmacoeconomic drugs vaginitisYu．2却on，，地眦 Women’sandChildren’s 110012，China ofPharmacy，the HospitalofShenyang，眦，咿ng，Lianning To thecost-effectivenessoffour intreatmentofbacterial 【Abstract】Objective drugs vaginitis investigate and clinicrationaluse．Methods361bacterial weretreatedwithlactobacillusva- improve drug vaginitisout-patients tab- effervescent effervescent ginal tablets(92cases)，lacidophilinvaginalcapsules(88cases)，shuangzuotaivaginal effervescent costand tablets(91 lets(90cases)，metronidazolevaginal cases)．Thetherapeuticect，drug therapeutic overall rateoflactoba- effectwereevaluatedcosteffectiveness7daftertreatment．R鹤IlItsThe by analysis response cillus effervescent effervescent vaginal tablets，lacidophilinvasinalcapsules，shuangzuotaivaginal tablets，metron- idazole effervescenttabletswere overall vaginal 78．26％，76．14％，83．33％and78．02％，respectively．Theresponse ratewasno differencebetweenfour metronidazoleeffervescenttabletshadthe s