运动终板药物注射治疗痉挛型脑性瘫痪的效果.pdfVIP

中国康复理论与实践2014年8月第20卷第8期ChinJRehabilTheoryPract,Aug.,2014,Vol.20,No.8 - 776 - DOI: 10.3969/j.issn. 1006-9771.2014.08.018 ·临床研究 · 运动终板药物注射治疗痉挛型脑性瘫痪的效果① 1,2 2 1 翟红印 ，许予明 ，谢晓明 [摘要] 目的 观察运动终板药物注射治疗痉挛型脑瘫患儿的效果。方法 230 例痉挛型脑瘫患儿分为对照组和观察组，每组 115例。对照组给予综合康复，包括功能训练、物理因子治疗及药物应用；观察组在此基础上加痉挛肌肉运动终板注射维生素B 和 1 维生素B12 。治疗前后采用粗大运动功能测试(GMFM)评价患儿功能区的运动功能，采用改良Ashworth 量表(MAS)评价痉挛程度， 采用CDCC 婴幼儿智能发育量表测定智力发育指数(MDI)和心理运动发育指数(PDI)。结果 治疗后，两组患儿的粗大运动功能明 显改善，MAS 分级明显降低，MDI 和PDI 评分明显增加(P0.01) ；且观察组均优于对照组(P0.05) 。结论 肌肉运动终板药物注射 能提高脑瘫患儿粗大运动功能，减轻痉挛，改善智力发育。 [关键词] 脑性瘫痪；痉挛；运动终板；药物注射；维生素B ；维生素B 1 12 Effect of Drug Injection in Muscle Motor Points on Spastic Cerebral Palsy ZHAI Hong-yin, XU Yu-ming, XIE Xiao-ming. Rehabilita- tion and Treatment Centre for Cerebral Palsy, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China Abstract: Objective To explore the effect of drug injection in muscle motor points on children with spastic cerebral palsy. Methods 230 children with spastic cerebral palsy were divided into control group and observation group, with 115 cases in each group. The control group received comprehensive rehabilitation including functional training, physical therapy and medicine, while the observation group re- ceived injection of vitamin B1 and vitamin B12 in muscle motor points in addition. They were assessed with Gross Motor Function Measure (GMFM), modified Ashworth Scale (MAS), mental development index (MDI) and psychomoter developmental index (PDI) of CDCC Infant Me Ntal Development Sca