磁共振对颅内静脉窦阻塞性疾病的诊断价值_医学论文.docVIP

磁共振对颅内静脉窦阻塞性疾病的诊断价值_医学论文 磁共振对颅内静脉窦阻塞性疾病的诊断价值_医学论文 作者：刘奉立 于本霞 苏续清 岳凤斌 邹萍 潘英华 　　［摘要］目的 探讨颅内静脉窦阻塞性疾病（CVSOD）在磁共振（MRI）不同成像方法中表现，特别是CVSOD直接征象的敏感性及特异性。方法 收集我院2001年12月～2004年5月经临床、手术证实的CVSOD病人共14例，对其MRI表现，主要是对不同成像序列的平扫、磁共振静脉成像（MRV）及增强扫描图像（CE-MRI）中的直接征象进行分析并随机抽取无CVSOD临床症状、有颅内静脉窦流空效应减弱征象的29例病人作为对照组进行对比分析。结果 在各种平扫成像序列中，除T 2 WI两组间信号强度差别无显著意义外，其余各序列，包括T1 WI、FLAIR、DWI以及MRV，两组间信号强度差别均有显著意义，以T1 WI和DWI像两组间信号强度差别最为显著（ uc = 2.764～5.729，P lt0.05）。在CE-MRI，两组间信号强度差别无显著意义，但在形态上有明显差别。结论在MRI平扫序列中， T 2 WI对CVSOD造成的流空效应减弱较为敏感，但特异性较差而T1 WI及DWI特异性较高。MRV、CE-MRI中，形态的改变较信号改变对诊断CVSOD具有更重要的意义。 　　［关键词］ 颅内静脉窦阻塞颅内静脉窦血栓磁共振成像诊断 　　 　　［ABSTRACT］ObjectiveTo investigate the manifestations of cerebral venous sinus occlusive diseases （CVSOD） with diffe- rent magnetic resonance imaging （MRI） methods， especially the sensitivity and specificity of the immediate signs of the disease. MethodsFourteen cases of CVSOD confirmed by clinical data or surgical operation in our hospital from December 2001 to May 2004 were reviewed. The direct signs on different MRI sequences of plain scan， on 2D-TOF-MR Venography （MRV） and on con-trast enhanced MRI （CE-MRI） were analyzed. Twenty-nine cases with decreased flow-void in sinuses were served as the controls. ResultsExcept for T2weighted image （T2 WI）， the signal intensities were significantly different between the two groups on most of the sequences of plain scan， including T1weighted image （T1 WI）， fast liquid-attenuation inversion recovery （FLAIR） sequence， diffusion weighted imag （DWI） and MRV. The differences were most significant in T1 WI and DWI. Although the difference in sig-nal intensity was not significant between the two groups on CE-MRI， the shape of the defect was markedly different between the two groups. ConclusionOn plain scan， T2 WI is sensitive to the decreased flow-void effect caused by CVSOD， but the signal change is less specific. T1 WI and DWI have the highest specificity in the diagnosis of the disease. On MRV and CE-MRI， the study of the profile change