蛋白质芯片制备及分析.pptVIP

蛋白质芯片 蛋白质芯片工作原理 芯片上固定的分子是蛋白质如抗原或抗体等。检测的原理是依据蛋白分子、蛋白与核酸、蛋白与其它分子的相互作用。 Protein Microarrays Are of Two Types Summary of Protein Chip Applications Outline 蛋白质芯片制备及分析 蛋白质芯片的分类 蛋白质芯片的应用 蛋白质芯片制备及分析 蛋白质芯片制备 载体 捕捉分子 载体的选择 载体材料符合下列要求： 载体表面必须有可以进行化学反应的活性基团； 使单位载体上结合的蛋白质分子达到最佳容量； 载体应当是惰性的，有足够的稳定性; 具有良好的生物兼容性； 捕捉分子 抗体分子 寡核苷酸 多肽 小分子配体 重组蛋白 NanoPrint? Protein Edition Microarrayer Deliverables specific to the Protein Edition NanoPrint NanoPrint Microarrayer Stealth 48 Micro Spotting Device(with extended collars) Multi-station wash, dry station and sonicator for Micro Spotting Pins to remove even the “stickiest” of proteins. Digitally controlled Plate and/or Slide cooling options Deliverables specific to the Protein Edition NanoPrint Digitally Controlled Humidity Chamber Hepa Filtered Microarraying Chamber ArrayManager software Deliverables specific to the Protein Edition NanoPrint A starter pack of consumables to get your started printing your samples immediately including: Microarray Microplates, SuperEpoxy,Substrates, SuperProtein Substrates, Protein Printing Buffer, and BlockIt. NanoPrint Microarrayer NanoPrint Microarrayer Linear drive systems providing universal microarraying platforms for printing a wide range of biomolecules onto glass substrates, slides and microplates. NanoPrint? Microarrayer is a robust and customizable platform for all microarray manufacturing applications regardless of the type of biomolecule. NanoPrint Microarrayer The NanoPrint? systems manufactures high quality, precision microarrays utilizing TeleChem’s ArrayIt brand patented and widely used, Professional, 946 and Stealth Style Micro Spotting Pins.? The NanoPrint uses superior linear drive motion control technology, and proprietary Warp1 controllers from Dynamic Devices.? NanoPrint Microarrayer The NanoPrint is compatible with all standard microarray surfaces made by ArrayIt and other vendors. Deliverables specific to the Protein Edition NanoPrint NanoPrint Microarr