多层螺旋CT定量研究慢性阻塞性肺疾病肺衰减值.pdfVIP

中国医学影像技术200生箜 鲞笙 塑 生 ! 受 ! ： ： ： ·◆．胸部影像学 QuantitativeMSCTstudyoflungattenuationinpatientswith chronicobstructivepulmonarydisease ZHANGJi ，yU 丁 一Z ，WUQ ，YENing ，CAOYang ，ZHANGJing ，ZHOUNing (1．DepartmentofRadiology，2．DepartmentofRespiratoryMedicine，GeneralHospitalofTianjin MedicalUniversity，Tianjin300052，China) [Abstract] Objective Toinvestigatetherelationshipbetweenlungattenuationandpulmonaryfunctiontest(PFT)results inDatientswithCOPD using 16slicespiralCT (16-SCT)．Methods Fifty COPD patientsunderwent16一SCT and PFT． Quantitativeanalysiswasperformedwithhistograms，andthemeanlungattenuation (MIA)，thepixelindex (PI)ofthe proportionsof1ungvolumeswithattentionvaluesbelow ～910HU and一950HU weremeasured．Thecorrelationsbetween M SCT measurementsandPFT resultswereassessed，anddifferencesofMLA ，PI一91。andPI一95oamongthegroupsOfthepa tientswithCOPD from stage0— 4wereevaluated．Results MLA ，PI．91。andPI．95。weresignificantlycorrelatedwithPFT re— suits．MLA，PI0andPIocorrelatedthemostcloselywithFEV1／FVC(％)whichreflectedairflow limitationandobstruc— tion．PI一95ocorrelatedcloselywithPFT results．Amongthegroupsfrom stage0—4，PI950reflecteddifferencesmoresensi— tivelythanMIA andPL91。．Conclusion QuantitativeMSCT studyof1ungattenuationcanassessthechangesofpulmonary parenchymainpatientswithCOPD bythree-dimensionalanalysis．PI一95oisarathersensitiveindexinquantitativestudyof pulmonaryparenchymalchangesinpatientswithCOPD． [Keywords~ Emphysema：Pulmonarydisease，chronicobstructive；Tomography，X—raycomputed 多层螺旋 CT定量研究慢性阻塞性肺疾病肺衰减值 张 洁 ，于铁链 ，吴 琦。，叶 宁 ，曹 杨 ，张 静 ，周 宁 (1．天津医科大学总医院放射科 ，2．呼吸内科 ，天津 300052) [摘 要] 目的 应用 16层螺旋CT扫描观察慢性阻塞性肺疾病 (COPD)患者肺衰减值与肺功能检查结果的相关关系。 方法 COPD患者共 5O例