Formation of novel protein-coding genes.pptVIP

Formation of novel protein-coding genes Level 3 Molecular Evolution and Bioinformatics Jim Provan De-novo formation of novel protein-coding genes Creation of simple structural elements such as a-helices, b-sheets and reverse turns seems to be rather trivial: So many alternative ways of forming these structures Have been “invented” independently several times Proteins with repetitive structure are most likely to arise de novo: Repetitive oligonucleotide sequences can expand, forming periodic protein structures: Collagen-like Leucine-rich repeat (LRR) Probably arose several times during evoluti