对氨基水杨酸异烟肼联合左氧氟沙星、丙硫异烟胺治疗复治结核临床疗效观察.pdfVIP

1048 临床肺科杂志2011年7月第16卷第7期 对氨基水杨酸异烟肼联合左氧氟沙星、丙硫异烟胺治疗 复治结核临床疗效观察 陈蕾 吴桂辉何畏何钟宓 【摘要】 查。结果57例中52例完成疗程，结束时痰菌阴转率82．7％，肝功异常率9．62％。2例因副反应停药，3例因治疗失败改个体 化方案。结论对复治肺结核患者采用2PaVPtAK(Sm)／16PaVPt方案治疗的效果满意，药物副反应小，该治疗方案值得临床推 广。 【关键词】结核；肺／药物疗法；对氨基水杨酸异烟肼；左氧氟沙星 Clinical of and tocureretreated analysisusingpara-aminosalicylicacid，levofloxacinprothionamide pulmonary tuberculosisCHEN Lei，WU Diseasesl，Sichuan Gui—hui，HEWei，HEZhong一盹．ChengduHospitalforInfectious Cheng— au61006j．China Toobserveandevaluatethetreatmenteffectofretreated tuberculosiscases 2PaVPtAK 【Abstract】Objective pulmonary byusing 57casesofretreated tuberculosisweretreatedwith (Sm)／16PaVPt 2PaVPtAK(Sm)／16PaVPt regimen．Methods pulmonary regimen from smear inthe thmonth． 2006to2009．The wereexaminedwith andliver 0、2nd、6th、12nd、18 patients sputum function，X—ray Reasults52easesfinishedthetrearnent them．the conversionratewas82．7％amd9．62％hadabnor- course．Amongsputumnegative malliverfunction．2cases treatmentduetosideeffects．3cases their dueto failure．ConclusionIt stoped changedregimen therapeutic is which clinical effectivetotreatretreated tuberculosiscaseswith deservesthe pulmonary 2PaVPtAK(Sm)／16PaVPtregimen expansion． 【Key therapy，Pasiniazide，Levofloxacin． word】Tuberculosis，pulmonary／drug 我国是