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水溶性低代聚酰胺胺-金纳米复合物的制备、光学性质和细胞染色实验研究.pdf
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Preparation, optical properties and cell staining of water
soluble amine-terminated PAMAM G2.0-Au
nanocomposites
*
Xia Jinlan , Fu Jindian, Nie Zhenyuan, Shen li
School of Resources Processing and Bioengineering, Central South University, Changsha 410083 ,
China
jl xia@
Abstract
The solution chemical and optical characteristics of formation of NH -PAMAM
2
G2.0-Au nanocomposites in the aqueous solution of amine-terminated
polyamidoamine dendrimer G2.0 (NH2-PAMAM G2.0) under various mole ratios
of Au(III)/PAMAM were studied by both UV-Vis spectrometry and
fluorospectrometry. The NH2-PAMAM G2.0-Au nanocomposites, with a type of
structure in which one Au nanoparticle was surrounded by several NH2-PAMAM
dendrimers, emitted strong bluish violet fluorescence, and were uniform, water
soluble and biocompatible as well as very stable in frozen conditions. The sizes of
gold nanoparticles in the nanocomposites were about 2.5nm and decreased with
increase of NH -PAMAM G2.0 concentration. The NH -PAMAM G2.0 played an
2 2
important role in being as host or micro-reactor for Au(Ⅲ) before Au(Ⅲ) reduction
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