脑梗死后急性期患者认知功能障碍与情感障碍的相关性研究.docVIP

脑梗死后急性期患者认知功能障碍与情感障碍的相关性研究 【摘要】目的 调查脑梗死后急性期患者认知功能障碍与情感障碍的发生率及探讨其相关性，以期能为脑梗死患者的病情早期康复治疗提供参考。方法 选取脑梗死后急性期患者150例（脑梗死组）、同期体检中老年人50例（对照组），脑梗死患者在入院后3d、对照组在体检时行美国国立卫生研究院脑卒中评估量表（NIHSS）、简易精神状态检查量表（MMSE）、Barthel指数（BI）、汉密尔顿抑郁量表（HAMD）21项版、汉密尔顿焦虑量表（HAMA）14项版调查。结果 脑梗死组认知功能障碍发生率、抑郁与焦虑发生率均高于对照组（P0.05），脑梗死组焦虑及抑郁严重程度明显高于对照组（P0.05）；脑梗死组患者HAMA、HAMD、BI评分均明显高于对照组（P0.05），MMSE、NIHSS评分低于对照组（P0.05），MIHSS评分与BI评分之间具有正相关（P0.05），与HAMA之间具有正相关（P0.05），与HAMD评分之间具有正相关（P0.05）；MMSE评分与NIHSS 评分之间具有正相关相关（P0.05），与BI评分之间具有正相关（P0.05），与HAMA之间具有负相关（P0.05），与HAMD之间具有负相关（P0.05）。结论 脑梗死后急性期患者认知功能障碍及情感障碍发生率明显增高，两者之间明显具有相关性。 【关键词】脑梗死；急性期；认知功能障碍；情感障碍 After cerebral infarction in patients with acute cognitive dysfunction associated with mood disorders research [Abstract] Objective To investigate in patients with acute cerebral infarction cognitive dysfunction and the incidence of affective disorders and to explore their relevance, in order for the condition of patients with cerebral infarction early rehabilitation reference. Methods acute cerebral infarction 150 patients ( cerebral infarction ) , 50 cases in the elderly examination period ( control group ) , cerebral infarction after admission 3d, when the line of the control group in the examination of the NIH Stroke Assessment scale (NIHSS), Mini-Mental state Examination (MMSE), Barthel Index (BI), Hamilton Depression Scale (HAMD) 21 items edition, Hamilton Anxiety Scale (HAMA) 14 items version of the investigation. Results cerebral infarction incidence of cognitive dysfunction , depression and anxiety, the incidence rate was higher (P0.05), cerebral infarction severity of anxiety and depression was significantly higher (P0.05); cerebral infarction patients HAMA, HAMD, BI scores were significantly higher (P0.05), MMSE, NIHSS score than the control group (P0.05), MIHSS score and a positive correlation between BI scores (P0.05), and HAMA a positive correlation between (P0.05), and a positive correlation between the HAMD score (P0.05); MMSE score and a positive