护肝宁片防治药物性肝损害的疗效观察.pdfVIP

护肝宁片防治药物性肝损害的疗效观察 张月娟8，陈铁光(北京市大兴区精神病医院，北京102600) 中图分类号R975+．5文献标识码B 文章编号1672—2124(2011)11—1032—03 摘要 目的：探讨护肝宁片防治抗精神病药致肝功能异常的疗效。方法：将204例患者以随机抽样法分为治疗组和对照组，分 (P0．05)。结论：护肝宁片具有明显的防治抗精神病药致肝功能异常的疗效，相比于葡醛内酯疗效更稳定。 关键词 护肝宁片；抗精神病药；肝功能异常 of Tabletsfor Liver Efficacy Drug—induced Huganning Injury ZHANG District 1 Hospital，Beijing02600， Yue-juan+，CHENTie—guang(BeijingDaxing Psychiatric China) ABSTRACT the of tabletsfor ofliverinduced OBJECTIVE：To exploreefficacyHuganning dysfunction by totalof204 were toreceiveeither tabletsor antipsychoticdrugs．METHODS：Apatientsrandomlyassigned Huganning tabletsfor8weeks．Theclinical andlevelsofalanine glucurolactone symptoms both werefollowedaftertreatmentfor and20 transaminase(AST)andglutamyltranspeptidase(GGT)ingroups 4，8 liverfunctioninboth aftertreatment withbefore weeks．RESULTS：The improvedsignificantly compared groups treatmentof4and8 no differencesinlevelsof were treatment(P0．05)．Afterweeks，theresignificant ALT，AST andGGTandthe of withliverfunction tonormalbetweenthetwo proportionpatients returning differenceswerenotedbetweenthetwo with toallofthelivefunctional however，significant groupsregard attheendof20 tabletshasremarkable forliver weeks(P0．05)．CONCLUSION：Huganningtherapeuticefficacy the induced a