利胆合剂治疗婴儿巨细胞病毒感染胆汁淤积性肝病120例临床观察.pdfVIP

利胆合剂治疗婴儿巨细胞病毒感染胆汁淤积性肝病120例临 床观察 鄢素琪 邓玉萍 汤建桥 熊小丽 江治霞 李红 武汉市儿童医院中西医结合科430016 摘要：目的观察利胆合剂加更昔洛韦西药治疗婴儿巨细胞病毒感染胆汁淤积性肝病的临床疗效。方法将 符合病例入选标准的240例患儿按收治顺序分为两组，治疗组 （120例）采用利胆合剂加更昔洛韦治疗， 对照组 （120例）给予更昔洛韦治疗，疗程均为2月。观察两组患儿治疗前后症状体征及肝功能、巨细胞 病毒感染指标变化情况。结果治疗组在改善临床症状体征和巨细胞病毒感染、肝功能检验指标上优于对 照组(p＜0.05，p＜0.0l)。重症患儿早期治疗 （年龄2月内）效果尤其明显。结论利胆合剂加用更昔洛韦 治疗婴儿巨细胞病毒感染胆汁淤积性肝病临床疗效肯定，对重症患儿或许能改变预后，中药还能有效减轻 治疗中的不良反应。 关键词：利胆合剂；巨细胞病毒感染；胆汁淤积性肝病 120casesclinicalobservationofLidanMixturetreatingoninfantcholestaticliverdiseasescausedby cytomegalovirusinfection XIONGXiao-liJIANGZi-xiaLIHongDepartmentof YANSu-qiDENGYu-pingTANGJian-qiao IntegratedTraditionalChineseandWesternMedicineofWuhanChildrenHospital (430016) AbstractObjectiveToobservetheclinicaleffectof LindaMixturecombined gancic-lovirtreatingon cholestaticliverdiseasescausedbycytomegalovirusinfection.Methods 240casesweredividedintotreatment groupandcontrolgroupaccordingtovisitingsequ-ence.ThetreatmentgroupwastreatedbyLidanMixture combinedganciclovir,whilecontrolwastreatedbyganciclovir,theobservationtimewas2months,Toobser-ve thechangeofthetwogrouppreandposttreatmentonsymptomandsign,liverfunction,testindexof cytomegalovirus.Results Treatmentgrouphad markedsignificanceonimprovementofsymptoms, signs,liverfunction,andtestindexofcytomegaloviruscompare-edwithcontrolgroup(p＜0.05,p＜0.01);Tosevere patients,earlytreatment(in2monthsaf-terdelivery)h-asabettereffect.ConclusionLidanMixture combined ganciclovirtherap-yoncholestaticliverdiseasescausedbycytomegalovirusinfectionhasadlefimiteclinical curativeeffect,maybechangeprognosisforseverepatients;maybereduceadversereactionintreatment e-ffectively. KeywordsLidanMixture;Cytomegalovirusinfection;Cholestaticliverdiseases 第二十九次全国中医儿科学术大会暨。小儿意染性疾病的中区药预防”培训班论文汇编 浅黄或灰白相间计3分，大便颜色灰白或先白后浅黄计5分；③小便颜色异常：变黄计1分，小便深黄计 肋下触肋下lcm计1分， 计5分；⑥次症：腹胀易吐；神疲身倦；食少纳呆；烦吵。按每