评估青年人蛋白尿的危险因素_医学论文.docVIP

评估青年人蛋白尿的危险因素_医学论文 评估青年人蛋白尿的危险因素_医学论文 【摘要】 目的 调查分析青年人肥胖的患病率及蛋白尿的危险因素。方法 回顾性分析2008年11月-2009年8月在福建医科大Ц绞舻谝灰皆禾寮熘行哪炅?0-39周岁的人群体检资料，资料包含姓名、性别、年龄、身高、体重、体重指数、收缩压、舒张压、肌酐、尿素氮、空腹血糖、尿酸、TG、TC、HDL、LDL、尿蛋白。分析该人群男女各自肥胖、蛋白尿患病率，各种因素与蛋白尿的关系。结果 在资料完整的2293例青年体检者中，男性肥胖患病率33.3%，蛋白尿患病率2.5%；女性肥胖患病率7.5%，蛋白尿患病率1.7%。经单因素、多因素回归分析显示肥胖、血压、血脂紊乱、高血糖、高尿酸与蛋白尿独立相关。结论 在小于40岁的青年人男性肥胖率是33.3%，女性肥胖率是7.5%，总的肥胖率22.0%，男女蛋白尿患病率分别是2.5%和1.7%，高血压、血脂紊乱、高血糖、高尿酸、肥胖是蛋白尿危险因素。 【关键词】 肥胖 青年人 蛋白尿 慢性肾脏病 【Abstract】 Objective: We investigated the associated risk factors of proteinuria in young adults. Methods: A total of 2340 subjects who were aged from 20 to 39 years and received health examination in The Frist Hospital of Fujian Medical Universty from November 2008 to August 2009 were enrolled in this study. The Information includes name, gender, age, height, weight, body mass index (BMI), systolic blood pressure, diastolic blood pressure, serum creatinine (SCr), blood urea nitrogen (BUN), fasting blood glucose, uric acid (UA), triglycerides (TG), total cholesterol (TC), high density lipoprotein (HDL) and low-density lipoprotein (LDL). To investigate the prevalence of obesity or proteinuria. The relationship between risk factors and proteinuria was analyzed. Results: The prevalence of obesity was 33.3%, proteinuria 2.5% in man. The prevalence of obesity was 7.5%, proteinuria 1.7% in women. Multivariate analysis revealed that hypertension、hyperglycemia、dyslipidemia、hyperuricemia and obesity were independently associated with proteinuria. Conclusion: The prevalence of obesity was 33.3%, proteinuria 2.5% in man. The prevalence of obesity was 7.5%, proteinuria 1.7% in women in healthy subjects younger than 40 years of age.The risk factors (hypertension、hyperglycemia、dslipidemia 、hyperuricema and obesity) were independently associated with proteinuria. 【Key words】 obesity young adults proteinuria chronic kindey disease 前言 在我国肥胖的人数，特别是肥胖男性，随着经济的发展越来越多。2002年中国居民营养与健康调查结果显示，中国成人超重率为22.8%，肥胖率为7.1%，分别为2亿和6000万人，与1982年，中