微弧氧化处理纯钛种植体表面在模拟体液中可诱导磷灰石沉积.pdfVIP

1554· · doi 10.3969/j.issn. 1673-4254.2013.10.33 J South Med Univ, 2013, 33(10): 1554-1556 基础研究 微弧氧化微弧氧化处理纯钛种植体表面在模拟体液中可诱导磷灰石沉积处理纯钛种植体表面在模拟体液中可诱导磷灰石沉积 1 1 1 2 田智慧 ，张 宇 ，王立超 ，南开辉 1 2 南方医科大学口腔医学院，南方医院口腔医院，广东 广州 510515；华南理工大学材料学院，广东 广州 510641 摘要：目的检测微弧氧化处理后的纯钛种植体表面体外矿化能力并且获得具有磷灰石涂层的种植体。方法 将微弧氧化处理 后获得的种植体浸泡在模拟生理溶液（SBF）液中，在不同时间点取出种植体，利用扫描电子显微镜（SEM）、X-射线衍射分析 （XRD ）、X-射线光电子能谱仪（XPS ）分析其诱导磷灰石的能力和沉积物的形貌及组分。结果 在SBF溶液中浸泡后，微弧氧化 处理后的纯钛种植体表面有大量的钙磷盐沉积，微弧氧化样品在SBF 中形成的矿化层以磷酸八钙（OCP）晶相为主，并含有一定 量的碳酸羟基磷灰石（CHA）。结论 经微弧氧化处理后的纯钛种植体可以在SBF 中很好的诱导钙磷盐的沉积能力，其表面的矿 化层主要由类似自然骨组织的低结晶度的CHA结晶层组成。 关键词：微弧氧化；钛种植体；生物活性表面；体外矿化 Apatite-forming ability of pure titanium implant after micro-arc oxidation treatment 1 1 1 2 TIAN Zhihui , ZHANG Yu , WANG Lichao , NAN Kaihui 1Stomatology Hospital of Nanfang Hospital; College of Stomatology, Southern Medical University, Guangzhou 510515, China; 2College of Material Science and Engineering, South China University of Technology, Guangzhou 510641, China Abstract: Objective To investigate the apatite forming ability of pure titanium implant after micro-arc oxidation treatment in simulated body fluid (SBF) and obtain implants with calcium phosphate (Ca-P) layers. Methods The implants were immersed in (SBF) after micro-arc oxidation treatment for different time lengths, and their apatite forming ability and the morphology and constituents of the Ca- P layers formed on the sample surface were analyzed using X- ray diffraction, scanning electron microscopy, X- ray photoelectron spectroscopy, and energy dispersive electron probe. Results After immersion in SBF, large quantities of Ca- P layers were induced on the surface of the samples. The Ca- P layers were composed of