Pediatric Oral Pathology Soft Tissue Lesion - 上海交通大学医学院 .docVIP

上海第二医科大学 教　　案 课程名称　儿童口腔医学　　　　　　　第8次课　　2006年03月17日 教师姓名 汪 俊 职称 副教授 教研室 口腔儿童教研室 教学时数 2学时 授课题目 Pediatric Oral Pathology Soft Tissue Lesion 教学对象 02级七年制 授课地点 101教室 教学方式 大课授课方式 本课的重点、难点及对策： Keystone：1 Acute pseudomembranous candidiasis (thrush) 2 Differenitating of Primary herpes simplex infection, Hand, foot，mouth diseaseHerpangina Teaching material: Pediatric Dentistey Second Edition Richard R.Welbury OXFORD UNIVERSITY PRESS Teaching aid：Multimedia  主要教学内容及时间分配： 1 Infection: 1.1 Viruses: 1) Herpetic infention: 2) Hand, foot，mouth disease Cause: Coxsackie virus A16 Signs and symptoms Prodrome: Fever, malaise, lymphadenopathy Skin lesion : Maculopapule(斑丘疹）on the hands and feet Oral lesion: vesicles ulceration Course: 10-14 days 3) Herpangina（疱疹性咽峡炎） Cause: Coxsackie virus A4 Signs and symptoms Light systemic reaction and prodrome B Vesicles in the tonsillar or pharyngeal region ulcers, no coalesce for large areas of ulceration C Short-lived 1.2 Bacteria 1) Staphylococcal infections impetigo 2) Streptococcal infection 3) Congenital syphilis 1.3 Fungi or protozoa（原生动物） Oral Candidiasis Candidiasis describes a group of yeastlike fungal infections involving the skin and mucous membranes. Classification of oral candidiasis Acute pseudomembranous candidiasis (thrush) 2) Acute atrophic candidiasis, 3) Chronic hyperplastic candidiasis, 4) Chronic atrophic candidiasis. Acute pseudomembranous candidiasis (thrush) Pathogens: Candida albicans. It’s a harmless commensal organism, but if there is a disturbance in the oral flora or a decrease in the immune defenses, it becomes opportunistic pathogen. Transmission: Vagina or infection from breast or feeding utensil Risk Factors: Low level of Antifungals substance Deficiency of myeloperoxidase (脊髓过氧化物酶) Low secretion of saliva Clinical features Age：Neonates and infants within 6 months Oral lesion: White patches oral mucosa, tongue Lesions develop into confluent plaques that rese