卵泡未破裂黄素化综合征58例临床治疗_临床医学论文.docVIP

卵泡未破裂黄素化综合征58例临床治疗_临床医学论文 卵泡未破裂黄素化综合征58例临床治疗_临床医学论文 【摘要】 目的 探讨多囊卵巢综合征(PCOS)促排卵治疗中出现的卵泡未破裂黄素化综合征(LUFS)的治疗措施。 方法 选择2006年1月～2007年12月在临沂市妇幼保健院生殖中心就诊的PCOS不孕症患者经促排卵治疗，对发生LUFS 58例患者35例给予卵泡穿刺(为穿刺组)，23例妇科检查机械性挤压法(为挤压法组)治疗，比较治疗后的排卵率、妊娠率以及中、重度卵巢过度刺激综合征(OHSS)的发生率。 结果 穿刺组排卵率为100 %(35/35)，妊娠率为31.4 %(11/35)，OHSS的发生率为2.9 %(1/35);挤压组排卵率为47.8 %(11/23)，妊娠率为8.7 %(2/23)，OHSS的发生率为13.0 %(3/23);两组妊娠率及OHSS发生率比较，差异无统计学意义;穿刺组排卵率高于挤压组，差异有统计学意义(0.001)。 结论 PCOS促排卵治疗中发生的LUFS给予卵泡穿刺术治疗效果肯定，是一种有效的治疗方法。 【关键词】 多囊卵巢综合征; 卵泡未破裂黄素化综合征; 不孕症; 卵泡穿刺; 妇科检查机械性挤压 　　【Abstract】 Objective To evaluate the treatment of luteinized unruptured follicle syndrome(LUFS) in patients with polycystic ovary syndrome (PCOS) in ovulation induction. Methods Fiftye divided into two groups. 35 cases(Group 1) were underwent ultrasounddirected follicular aspirations and 23 cases(Group 2) were give gynecological examination with mechanical extruding. Results All 35 cases in group 1 were successful in ovulation induction. Eleven pregnancies and one moderate ovarian hyperstimulation syndrome (OHSS) occurred in group 1, resulting in a pregnancy rate of 31.4 %, and an incidence of moderate OHSS 2.9 %. Two pregnancies and 11 ovulation induction developed in group 2 with 3 moderate OHSS, resulting in a pregnancy rate of 8.7 %, an incidence of ovulation 47.8 %, and an incidence of moderate OHSS 13.0 %. No severe cases of OHSS were noted in either of the two groups. Comparison of the therapeutic effects between the two groups showed significant difference (0.001), with higher incidence of ovulation in group 1 than in group 2. No significant differences were noted in pregnancy rate and incidence of moderate OHSS (Pgt;0.05). Conclusion The therapy of ultrasounddirected follicular aspirations is effective in treating LUFS with PCOS in ovulation induction. 　　【Key words】 Polycystic ovary syndrome;Luteinized unruptured follicle syndrome;Infertility; Follicular aspiration; Gynecological examination with mechanical extruding 　　卵泡生长但无排卵发生，形成未破裂卵泡黄素