云克配合^131Ⅰ治疗Graves病合并Graves眼病的近期疗效.pdfVIP

一中旦堡兰 堡垫 !生箜 !鲞第10期 ChinJMedImagingTechn01，2008，vbi24，No10 ．：◆核医学 Shortterm therapeuticeffeciencyofYunkecombinedwith 3Ion GravesdiseasecomplicatedwithGravesophthalmopathy WEJZhi—xiao ，L Jun—hong，QIN Wei～WU。LIYa—fan (DepartmentofNuclearMedicine，theFirstAffiliatedHospitalofGuangxiMedical University，Nanning530021，China) ~Abstraet] 0bjective ToevaluatetheshorttermtherapeuticeffeeieneyofYunke( Tc—MDP)applieationcombinedwith IonGravesdisease(GD)complicatedwithGravesophthalmopathy (G0)．Methods Ninety-fivepatientswithGDcompli— catedwithGO wererandomlydivided intotrialgroup (57 cases)andcontrolgroup (38cases)．Thepatientsinthetrail groupweregivenYunketreatmentafter5— 7daysof “Itreatment．Thetreatmentconsistsofthreecourses：courseone10 — 15days(4groups，5mg／group)withYunkeintravenousdripdaily，coursetwo15--20days(2groups。5mg／group)and coursethree15—20days(onegroup，5mg)．Thepatientsinthecontrolgroupdidnotacceptanydrugafter Itreatment． Results Thenotablerates，effectiveratesand ineffectiveratesin thetrialand controlgroup was38．6 and 13．2 ， 43．9 and23．7 ，17．5％and63．1 ，respectively．TheresultsofthetWOgroupsweredifferentstatistically(PO．01)． Thelighterthedegreeofophthalmoptosiswas，thebetterthetherapeuticefficacyintrialgroupwas．Conclusion Thetreat— mentofYunkecombinedwith 0IiSmoreeffectivethansingle0IinthetreatmentofGD complicatedwithGO． [Keywords] Yunke；Gravesophthalmopathy；Thyroidgland 云克配合nI治疗 Graves病合并Graves眼病的近期疗效 韦智晓 ，李俊红，覃伟武，李亚范 (广西医科大学第一附属医院核医学科，广西 南宁 530021) [摘 要] 目的 评价云克 ( Te—MDP)配合”I治疗Graves病(GD)并Graves眼病 (G0)的近期疗效。方法 将”I治疗 的95例 GD和GO患者随机分为 2组，研究组 57例，于…I治疗后 5～7天采用云克治疗 GO，第 1疗程 1O～15天，每天静 脉推注云克4组 (每组5rag)，第 2疗程 15～2O天，每天静脉推注云克2