基于选择牵连效应的标记性状关联分析方法简介.pdfVIP

HEREDITAS (Beijing) 2007 年7 月, 29(7): 881888 ISSN 0253-9772 DOI: 10.1360/yc-007-0881 / , , 100081 摘要: , , , / , , QTL , 关键词: ; ; ; Identification of important genes by marker-trait association analy- sis based on hitchhiking mapping YOU Guang-Xia, ZHANG Xue-Yong Key Laboratory of Crop Germplasm Biotechnology, MOA, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China Abstract: Most agronomic traits such as yield, quality and stress-tolerance of crops are quantitative traits. It is not easy to dissect genetic basis of these traits because they are controlled by multi-genes that are affected by environmental factors. Hitchhiking mapping offers a new method for identifying of loci controlling those traits and assessing their allelic variations. Marker-trait association analysis based on the hitchhiking effects will play an important role in dissection of complex traits. Combination of quantitative trait loci (QTL) mapping with marker-trait association analysis will facilitate dissection of complex traits, resulting in important information and markers for molecular breeding by design in crops. In this review, we presented a brief introduction of hitchhiking effects, marker-trait association analysis and practical considerations. Keywords: quantitative traits; linkage disequilibrium (LD); hitchhiking effect; association analysis ,