利奈唑胺对奴卡菌属感染中的应用文献计量分析.pdfVIP

利奈唑胺对奴卡菌属感染中的应用文献计量分析 1 1 1 2 2 2 2 刘旭 ，蔡芸 ，白艳，梁蓓蓓，白楠 ，王瑾* ，王睿 （解放军总医院1.临床药理研究室; 2.药物临床研究中心，北京 100853 ） [摘要] 目的：分析截止至2013 年 8 月利奈唑胺在奴卡菌属感染方面的相关文献，为抗感染工作 领域研究者提供参考。方法：检索PubMed 、SCI、Embase 、中国知网等数据库，采用文献计量学方法， 对纳入文献的年代、通讯作者、文章类型、研究内容、被引文频次等进行统计分析。结果：文献共 349 篇，符合要求 163 篇。文献量总体呈现上升趋势，主要文章类型为病例报告 77 篇，占总体文献数量的 49.68% 。其中，共有27 例以利奈唑胺治疗奴卡菌属感染病人。单篇文章被引频次最高为 101 次，研究 内容分析包括奴卡菌属感染及基础研究分析，奴卡菌属临床诊断等。结论：目前，利奈唑胺对奴卡菌属 感染的应用效果主要体现在病例报告中，还需高质量的随机对照临床试验确证其治疗效果。 [关键词]：利奈唑胺；奴卡菌；文献计量分析 Bibliometric analysis of treatment with linezolid for nocardia infection 1 1 1 2 2 2 2 LIU Xu , CAI Yun , BAI Yan , LIANG Bei-bei ,BAI Nan ,WANG Jin* ,WANG Rui (PLA General Hospital,1.Department of Clinical Pharmacology; 2. The Center of Medicine Clinical Research ,Beijing 100853,China) [Abstract] Objective:To investigate the treatment with linezolid for nocardia infection over 2013 based on a bibiometric approach. Method:We searched PubMed, SCI, Embase, CNKI. The amount of year, corresponding author, research institutions, type of literature, contents and cited frequency were analyzed. Outcome:A total of 349 papers,163 papers were included. The number of papers published showing an overall upward trend and 49.68% in total papers of 77 case reports are the main type of literature. There are 27 cases of treatment nocardia infection with linezolid. The highest cited frequency of paper is 101.Analysis of cause of infection, basic research and diagnosis. Conclusion:The effect of treatment with linezolid for nocardia infection is suggested by case report. Now, it is necessary that high quality randomized controlled clinical trials confirmed its therapeutic e