中等强度跑台运动和补充雌激素对去卵巢雌性大鼠ENaC+γ和骨量的影响研究.pdfVIP

Keywords:ovariectomizedrat;moderate intensity exercise;PKGⅡ TheeffectofmoderateintensityTreadmill exerciseandestrogenontoENaCgammaand bonemassinfemaleovarieomizedratsimpact study WenrongWangYangliu ZhiqiangWangXiaoqi GaoLuZheng XiaohongChen Beringscapitalinstituteofphysicaleducation 100191 Objective: through the establishment of rat osteoporosis models, with moderate intensity treadmillexerciseintervention,effectsofexerciseon ENaC-α,ENaC-rinfluenceandeffectofbone mass,providethebasisforclarifyingtheinfluence ofexerciseonbonemass.methods:Femalerats (threemonthsold)weredividedinto5groups, includingCON,OVX+C,OVX+E,SHAM,each groupincltidingl0;Separatelyinonemonth,two months,threemonthsmoderateintensityexercise. from16to90years. Keywords:ovariectomizedrats;exercise estrogen; bonemass;ENac;mRNA Relation ofPeripheral 5-hydroxytryptamine LevelstoBoneDensityandBiochemicalIndexof BoneMetabolisminHuman Luchen-Kang1，2 Weiming-Deng1 1.Huaqiao SuperiorMedical Center, Gerneral HospitalofGuangzhouCommand,Guangzhou Guangdong,China 2.GuangzhouUniversityofTraditionalChinese Medicine,Guangzhou,Guangdong,China Objective:Toanalysistherelationofperipheral 5-hydroxytryptaminelevelstobonedensityand biochemicalIndexofbonemetabolismsuchas serumProcollagenIN-terminalPropeptide(PINP)、 3-Crosslaps、 Parathyroid Hormone(PTH) and 25-hydroxyvitamin D (25(OH)D) in Human.Methods:(Werecruited533peoplefrom anage-stratifiedrandomsampleofGuangzhou, Keywords:5-HT;BMD;PINP;β-Crosslaps;PTH; Chinaresidents.Atlasttheanalysiswasbasedon 25(OH)D;Osteoporosis 423people,allofthemwerepatientsoftheGerneral HospitalofGuangzhouCommandbetweenMay 2011toDecember2012.Thesamplespannedages 降，补充外源性17β-雌二醇后，三项指标均显著 的影响，为骨质疏松的预防、减缓及诊断提供实验 增加；运动组子宫重量和子宫重量指数无显著变 依据。 化，但血清E2水平显著增加。 关键词：17β-雌二醇 ;运动 ;去卵巢大鼠 ;骨组 织 ;E