82支原体感染的肺外表现及发病机制.pdfVIP

·综述· 儿童肺炎支原体感染的肺外表现及发病机制 孟珊珊(综述) 张海邻(审校) 【摘要】肺炎支原体(mycoplasmapneumoniae，MP)是儿童呼吸道感染的常见病原，占儿童社区获得 性肺炎的10％一40％。MP感染表现为一系列的症状和体征，可无症状，也可有致死性肺炎或肺外并发症 的发生。肺外表现的机制尚未十分清楚，分为直接型、间接型、血管闭塞型三种。MP感染的肺外表现涉及 全身多个系统，如神经系统、心血管系统、血液系统、皮肤及其他系统。该文对MP肺外表现及发病机制进 行阐述，以提高临床医生对MP肺外表现的认识。 【关键词】肺炎支原体；儿童；肺外表现；发病机制 manifestationsand of infectioninchildrenMENG Extrapulmonary pathogenesisMycoplasmapneumoniae Children’S Shan—shan，ZHANGHai—lin．DepartmentofRespiratoryDiseases，AffiliatedYuying Hospitalof WenzhOUMedical College，Wenz幻u325027，China oneofthemostcommonof 【Abstract】Mycoplasmapneumoniae(MP)is agentscommunity-acquired inchildren．MPhasbeen in10％～40％ofcasesof and pneumonia reported community-acquiredpneumonia an incidence a showseven infections of and higher during displayspectrum signs，ran- epidemics．MP symptoms from infectiontosevereand fatal or manifestations． ging asymptomatic potentiallypneumoniaextrapulmonary The of manifestationsremain unknown．Thisreviewclassifies ex廿apulmonary largely extrapulmo— pathogenesis manifestationsduetoMPinfectionintothree andvascularocclusion nary categories：directtype，indirecttype manifestationsinclude andother t)，pe．These neurological，cardiac，hematological，dermatologicalsymptoms．This article anoverviewof manifestationsand ofMPinfectionsinchildrento presents extrapulmonary pathogenesis the for improvecomprehensiondiagnosis． 【Keywords】Mycoplasma pneumoniae；Children；Extrapulmonaryma