ThalamicStrokeandDisorderedSleep：丘脑卒中和睡眠紊乱.pptVIP

Thalamic Stroke and Disordered Sleep Kenneth C. Sassower, M.D. Sleep Disorders Unit Massachusetts General Hospital Hypersomnia After Thalamic Stroke: “Traditional” Concept EDS due to insufficient arousal Interruption of NE and DA activating impulses ascending from brainstem RF to thalamus Diurnal sleep behavior composed of NREM stage I (drowsy) sleep; no deeper sleep Night sleep mechanisms preserved Disturbance of wakefulness: “De-aroused” state rather than true hypersomnolence Hypersomnia After Thalamic Stroke: “Revised” Concept Thalamus has a key role in sleep production (as well as arous