正品威灵仙与贵州地区习用品主要药效的对比研究.pdfVIP

2009 27 8 Vol127, No18, 2009 Journal of Sichuan of Tra itional Chinese Me icine # 53 # p p 正品威灵仙与贵州地区习用品主要药效的对比研究X 钱海兵 陈秀芬 孙宜春 黄 婕 王祥培 ( 550002) : 目的: 通过正品威灵仙与贵州地区习用品种柱果铁线莲和 木通主要药效学的对比研究, 对柱果铁线莲和 木通与正品威灵仙进行药效质量评价方法: 采用二甲苯致小鼠耳肿胀实验角叉菜胶致小鼠足肿胀和小鼠棉球肉 芽肿等实验进行抗炎实验, 采用醋酸扭体法进行镇痛实验结果: 柱果铁线莲和 木通与正品威灵仙对小鼠足肿胀 小鼠耳肿胀和棉球肉肿等炎症和对醋酸引起的扭体反应具有明显的抑制作用; 且柱果铁线莲对小鼠足肿胀的抑制作用 和 木通对醋酸引起的扭体反应的抑制明显优于相同有效剂量的正品威灵仙结论: 柱果铁线莲和 木通作为威灵仙 在贵州地区应用具有 一定的药效学基础 : 正品威灵仙 柱果铁线莲 木通 质量评价 : R282175 : A : 1000- 3649 (2009) 08- 0053- 03 Comparison of Pharmacodynamics of Clematis Chinensis and it. s Conventional Varieties Used in Guizhou/ Qian H aibing Cheng X iuf en S un Yichun H uang Jie Wang X iangp ei M Guiyang College of Traditional Chinese Medicine ( Guiyang Guizhou 55002 China) Abstract: Objective: To estimate the quality of Clematis Chinensis an it. s Conventional Varieties cultivate an use in Guizhou inclu ing Clematis uncinata an Clematis finetiana by the stu y of primary pharmaco ynamics1Metho s: Anti- inflammation ef- fect of Clematis Chinensis an it. s Comfusable Varieties use in Guizhou were observe by mouse auricle swelling test in uce by xy- lene, mouse pe al swelling test in uce by carrageenin an cotton granuloma test in mouse1 analgesic action observe by mouse acetic- aci - in uce twisting test1Results: All of them can re uce pe al swelling, aurical swelling an cotton granuloma of mouse, an in- hibit twisting response of mice obviously1But in the same ose, Clematis uncinata is more efficient in mouse pe al swelling test an Clematis finetiana in mouse acetic- aci - in uce twisting test then Clematis Chinensisin1 Conclusion: Both Clematis uncinata an Clematis finetiana cultivate an use in Guizhou can be use