步长稳心颗粒对老年舒张性心力衰竭合并阵发性房颤患者P波离散度的影响.pdfVIP

步长稳心颗粒对老年舒张性心力衰竭合并 阵发性房颤患者P波离散度的影响 张明亮 靖树新 张焕轶 目的研究稳心颗粒对老年舒张性心力衰竭合并阵发性心房颤动(PAF)患者P波最大时限 (Pmax)、P波离散度(Pd)的影响。方法将115例老年舒张性心力衰竭合并PAF患者作为房颤组，随机分为 两组：A组56例为常规治疗组，B组59例在常规治疗的基础上加用稳心颗粒。同时以54例老年舒张性心力 衰竭不伴PAF患者作为对照组。比较房颤组及无房颤组以及A、B组间治疗前后Pmax及Pd的变化。 结果房颤组Pmax及Pd均高于非房颤组 （均P＜0.01），治疗前A、B两组Pmax及Pd差异均无统计学意义 （均P＞0.05），治疗后B组房颤发作次数明显减少，Pmax及Pd较治疗前均明显缩短，与A组比较差异均有统 计学意义 （均P＜0.01）。结论老年舒张性心力衰竭合并PAF者较无PAF者Pmax及Pd增大，步长稳心颗 粒治疗老年舒张性心力衰竭合并PAF可缩短Pmax及Pd，减少房颤发作次数。 舒张性，心力衰竭；阵发性，心房颤动；P波离散度；步长稳心颗粒；老年人 TheeffectofBuchangwenxinparticleondispersionofPwaveinelderpatientswithdiastoliccardiacdysfunc tionandparoxysmalatrialfibrillation ZHANGMing-liang* JINGShu-xinZHANGHuan-yi.*Departmentof Cardiology,TheCentralHospitalofTaian,Taian,Shandong271000,China Objective ToinvestigatetheeffectofBuchangwenxinparticlesinmaximumPwave(Pmax),dis persionofPwave(Pd)ofelderpatientswithdiastoliccardiacdysfunctionandparoxysmalatrialfibrillation(PAF). Methods 115elderpatientswithdiastoliccardiacdysfunctionandPAFwererandomlydividedintotwogroups: groupAreceivedtheroutinedrugtherapy,andgroupBreceivedBuchangwenbxinparticleswithroutinedrugtherapy. Another54elderpatientswithdiastoliccardiacfunctionbutwithoutPAFwasselectedascontrolgroup.Changesin PmaxandPdwerecomparedbetweengroupswithorwithoutPAFaswellassubgroups.Results PmaxandPdwere widerinPAFgroupthannoPAFgroup(allP＜0.01).TherewasnodifferencebetweengroupAandBinPmaxand Pd(allP＞ 0.05),andtherewerelessatrialfibrillationaswellasshortenedPmaxandPdingroupB,whichwassig nificantlydifferentwithgroupA(allP＜0.01).Conclusion PmaxandPdwerewiderinelderpatientswithdiastolic cardiacdysfunctionandPAFthanthosewithoutPAF,andBuchangwenxinparticlescouldshortenPmaxandPdand reducetheattacksofatrialfibrillation. Diastoliccardiacdysfunction;Paroxysmalatrialdefibrillation;DispersionofPwave;Buchang wenxinparticles;Elderpatients 10.3760/cma.j.issn.1008-6706.2011.20.010 271000山东省泰安，泰安市中心医院心内科 （张明 亮、张焕轶），老年保健科 （靖树新） 万方数据