基于_估计校正值低场功能磁共振成像分析方法.pdfVIP

第31 卷第2期 东 北 大 学 学 报 ( 自 然 科 学 版 ) Vol31, No. 2 2 0 10 年 2 月 Journal of Northeastern U niversit ( Natural Science) Feb. 2 0 1 0 1 1 1 2 杨 萍 , 何砚发, 王金星 , 于 兵 ( 1. , 110004; 2. , 110004) : (fMRI) , ( voxelbased morphometr , V BM) , , , V BM , , , fMRI : (fMRI) ; ; ( VBM) ; ; : R 445. 2 : A : 20 10) 020 16503 An Analysis Method Based on Correction of Estimated Value of for fMRI at Low Field 1 1 1 2 YA N G P ing , H E Yanf a , WA N G Ji nx ing , Y U B i ng ( 1. School of Sciences, Northeastern Universit , Shen ang 110004, China; 2. Shengjing Hospital of China Medical Universit , Shen ang 110004, China. Correspondent: YA NG Ping , Email: angp @ neusoft. com) Abstract: Proposes an effective anal sis method to decrease the interference effect of nonbrain signals on the functional magnetic resonance imaging ( fMRI) at low field, b which the activated area of the brain can be located precisel . The method combines the image segment method based on a deformable surface model w ith the vox elbased morphometr ( VBM) . The extracted brain tissue is taken as an explicit mask. Then, an anal sis mask is constructed to correct the estimated value of the parameter in general linear model ( GLM) , thus making the statistical inference just available to the brain tissue. The practical application revealed that the method proposed can effectivel eliminate the pseudoactivated area generated b the changes of the signals from background, skull and scalp and improve the reliabilit and precision of