Uterine amp; Ovarian Cancer.ppt

Uterine Ovarian Cancer Uterine Cancer Atypical Hyperplasia From hyperplasia to endometrial cancer Prevalence Incidence Causes Risk factors Detection Treatment Ovarian Cancer Risk factors Symptoms Detection Treatment I. Endometrial Cancer – Uterine Cancer Endometrial cancer usually begins in the lining of the uterus (endometrium). It is sometimes called uterine cancer. Vast majority are adenocarcinomas – commonly detected during perimenopause but there are other cells in the uterus that can become cancerous — such as muscle or myometrial cells. A. Atypical Hyperplasia = abnormal tissue growth simple hyperplasia without atypia = a proliferation of cells, but the basic structure of the endometrium is relatively unchanged complex hyperplasia without atypia = individual cells may be enlarged, but the internal makeup of the cells is considered to be normal.? However, the cells have proliferated to the point where the normal structure of the endometrium is interfered with.?? Hyperplasia with atypia = precancerous, Approximately 25-30% of hyperplasia in this category will progress to endometrial cancer. B. From hyperplasia to endometrial cancer C. Prevalence Incidence ACS predicts that 41,200 American women will receive a diagnosis of “uterine” endometrial cancer this year, making it the fourth most common cancer found in women — after breast cancer, lung cancer and colon cancer. Although this cancer is 40% more common in white women, black women are nearly twice as likely to die from it. D. What causes endometrial cancer? E. Risk Factors obesity -- particularly being more than 50 pounds overweight (fat tissue can convert other hormones in the body into estrogens) type 2 diabetes - some data suggest that women who have diabetes, whether theyre obese or not, are at greater risk of endometrial cancer early menstruation (periods starting before age 12) late menopause (after age 52) nulliparity (never having given birth) or a history of infertility (an inabili