超声引导经皮微波治疗肝癌32例临床分析_朱献忠.pdfVIP

全科医学临床与教育 2007 年3月 第 5卷第2期 Clinical Education of eneral Practice Mar.2007, Vol.5,No.2 ·113 · ·临床研究 · 超声引导经皮微波治疗肝癌32 例临床分析 朱献忠 蒋天安 徐祖贤 周伶 王 余小玲 [摘 要] 目的 探讨超声引导经皮微波治疗肝癌的技巧、方法,评价其对肝癌的临床疗效。方法 在超声引 导下利用穿刺架引导结合徒手进针法,对32例患者47个瘤体于60～80W、10～20min及一针至多针的局部微波 治疗。结果 随访8～56个月,47个瘤体中,肿瘤缩小率达95.64%,其中缩小50%达31.91%,螺旋CT增强扫 描显示完全无强化率占74.47%;治疗后AFP 下降至正常占76.48%(13/17),19个病灶进行穿刺活检,14个病灶 呈完全坏死占73.7%;治疗后1年、2年、3年、5年生存率分别为93.94%、80.99 %、72.23%、72.23%, 未见明显 的副作用和其他严重并发症。结论 超声引导微波凝固治疗肝癌疗效明显,定位精确,副作用小。 [关键词] 超声引导;微波治疗;肝肿瘤 Ultrasound uided ercutaneous microwav e coa ulation thera for liver carcinoma :32 cases clinical anal sis g p g py y ZHUXianzhon , JIAN Tianan, XUZuxian, ZHOU Lin, WAN Qin, YUXiaolin.De artment of Ultrasound, Zhe- g p ian Jinhua uan fu Hos ital, Jinhua 321000, China j g g p 【Abstract】Ob ectiv e To investi ate the method of ultrasound uided ercutaneous microwave coa ulation thera j g g p g py (PMCT), and to evaluate the efficac of PMCTfor atients with liver carcinoma.Methods Puncture frame combined y p with free-handed method was used, 32 patients with 47 tumor nodules underwent sonographically guided PMCT with 60～80W, 10～20min one or many coagulation.Results Among the 47 nodules in 32 patients with liver carcinoma , a follow-upof 8～56 months demonstrated that the lesions became smallerin 95.64%, andamongthem 31.91%became smaller more than 50%.35 tumors (74.47%)showed no enhancement on contrast-enhanced.AFP level decreased in 17 and became normal in 13(76.48%).A post-treated biopsy on 19 lesions showed complete destruction of tumor in 73.7%.The survival rate of 1,2, 3 and 5 years were 93.94%,80.99%