围绝经期综合征和神经递质_5_羟色胺_相关性的临床研究进展_李贺琦.pdfVIP

第 29 卷 第 2期 Vol. 29 No. 2 2 0 1 1年 2 月 CH INESE ARCH IVES OF TRAD ITOI NAL CH INESE M ED CI INE Feb. 2 0 1 1 ( 5 - ) 1 2 李贺琦 , 指导: 陈霞 ( 1. , 2 10029; 2. , 2 10001) : 目的: 探讨目前国内外有关血清 5- 羟色胺( 5- HT) 与围绝经期 合征临床症状的相关性的机制, 及其与雌激素治疗的关系, 和中医中药对 5-羟色胺影响的动物实验研究方法: 检索近几年来国内外运用中西 医疗法治疗围绝经期 合征, 及其与 5-羟色胺相关性的临床研究成果结果: 围绝经期患者血清 5- 羟色胺水 平异常, 出现烘热汗出, 失眠等临床症状, 经雌激素或中医中药治疗, 围绝经期症状得到改善结论: 雌激素及中 医中药对围绝经期 合征患者血清 5- 羟色胺水平有显著性调节作用 : 围绝经期 合征; 5- 羟色胺; 雌激素; 中医中药 : R285. 5 : A : 1673- 77 17( 2011) 02- 0375- 03 Climacteric Syndrome andNeurotransm itters ( 5 - HT) Correlation of Clinical Research 1 2 L IH e-q i, dvisor: CHEN X i ( 1. N njing U n iversity of Tr dition lCh in eseM edicine, N njing 210029, Ji ngsu, Ch in ; 2. N njing TCM H ospit l, N njing 210001, Ji ngsu, Ch in ) Abstrac:t O bj ect iv es: T o investig te the current dom estic nd intern tion l the serum of 5 - hydroxytrypt m ine ( 5- HT) nd clmi cteric syndrom e clinic l relev nce of the m ech nism nd role of estrogen ther py rel tionsh ip, nd tr di- tion l Chinesem edicine on the 5 - HT effects expermi ent l study.M ethod s: A se rch t hom e nd bro d in recent ye rs the use of TCM tre tment of permi enop us l syndrom e, nd w ith 5 - HT rel ted clinic l rese rch. R esults: M enop us l P tients 5 - HT bnorm lities of rehe t nd sw e ting, insom ni nd other sym ptom s by estrogen or Ch inese m ed icine tre tm en t of permi enop us l symptom s mi proved. Conclusion: Estrogen nd tr d ition l Ch inese m ed icine on p tients w ith permi enop us l syndrom e of 5 - HT w s sign ific nt regu l tor