肝移植术后受者焦虑状况调查和病因探讨.docVIP

肝移植术后受者焦虑状况调查及病因探讨 　　作者：陈规划,汪根树,陆敏强,杨扬,蔡常洁,易　　作者单位： 广州，中山大学器官移植研究所、中山大学附属第三医院肝脏移植中心 　　【摘要】目的 调查肝移植术后受者的焦虑状况并探讨其病因。方法 研究对象为2006年3月在本中心门诊随访的肝移植受者105名。采用汉密尔顿焦虑量表对研究对象进行问卷调查。结果 105例肝移植受者可能有焦虑、肯定有焦虑、肯定有明显焦虑和有严重焦虑的发生率分别为45.7%(48/105)、15.2%(16/105)、7.6%(8/105)和0(0/105)。大学文化程度、高中和中专文化程度、初中及以下文化程度肝移植受者焦虑发生率分别为15.8%(6/38)、27.6%(8/29)和26.3%(10/38)，三者间差异无统计学意义(P0.05)。60岁及以上、50～59岁、40～49岁和20～39岁肝移植受者焦虑的发生率分别为30%(6/20)、18.8%(6/32)、29.6%(8/27)和15.4%(4/26)，四者间差异无统计学意义(P0.05)。原发病为慢性乙型肝炎(重型)、乙型肝炎后肝硬化、原发性肝癌合并肝硬化和其他的肝移植受者焦虑发生率分别为19.2%(5/26)、22.9%(8/35)、24.3%(9/37)和28.6%(2/7)，四者间差别无显著性(P0.05)。术后0～180 d、180～365 d、366～730 d和730 d的肝移植受者焦虑发生率分别为35.7%(5/14)、17.9%(5/28)、22.2%(12/54)和22.2(2/9)。结论 肝移植术后受者有较高的焦虑发生率。肝移植受者的精神心理健康应受到关注，以进一步提高肝移植受者的生存质量。 　　【关键词】 肝移植; 焦虑 　　【Abstract】 Objective To investigate the anxiety of liver transplantation recipients and discuss its etiology. Methods The study objects included 105 liver transplantation recipients (101 males and 4 females) at age of (47.5±16.3) years who were followed up in our outpatient department on March 2006. The anxiety was investigated by using Hammilton anxiety scale via questionaire. Results The rate of probable anxiety, definite anxiety, obvious anxiety and serious anxiety in 105 liver transplantation recipients was 45.7% (48/105), 15.2% (16/105), 7.6% (8/105) and 0 (0/105) respectively. The rate of anxiety in recipients with bachelor, high school and middle school or less degree was 15.8% (6/38), 27.6% (8/29) and 26.3% (10/38) , with no statistically significant difference (P0.05). The rate of anxiety in recipients aged above 60 years, 5059 years, 4049 years and 2039 years was 30% (6/20), 18.8% (6/32), 29.6% (8/27) and 15.4% (4/26) respectively, with no statistical difference (P0.05). The rate of anxiety in recipients with undergoing disease of severe chronic hepatitis B, liver cirrhosis secondary to hepatitis B, primary liver cancer complicated by liver cirrhosis and other diseases was 19.2% (5/26), 22.9% (8/35), 24.3%