泄浊解毒方对溃疡性结肠炎大鼠NO+和NOS的影响.pdfVIP

mucosa .the chemical assay of NOSactivity in the rats ’serum and colonic mucosa .Result:NO and NOS in the UC serum and colonic mucosa was significantly higher. Xie-zhuo Jie-du Decoction can significantly reduce the expression of NO and NOS in the UC rats ’serum and colonic muco- sa.Conclusion: Xie- zhuo Jie- du Decoction has good and reliable therapeutical effect on ulcerative colitis, and its mechanism of action may be related to decreasing the expressions of NO and NOS in the UC rats ’ serum and colonic mucosa. 溃疡性结肠炎 （UC）是一种发生于结肠粘膜的慢性非特异性炎性 疾病。其病因和发病机制尚不十分清楚，目前许多研究表明其发病机 制与环境