拉莫三嗪单药治疗新诊断的癫疒间患者两年保留率研究.pdfVIP

● 论著 ● 拉莫三嗪单药治疗新诊断的癫痫患者 两年保留率研究 郑乃智，王敏，沈红卫，卢幸明 [摘要]目的：研究拉莫三嗪单药治疗新诊断的癫痢患者两年保留率。方法：结合门诊随访和 电话回访．复习138倒新诊断的癫痢患者应用拉莫三嚓治疗两年的情况。结果：拉莫三嘹单药治疗新诊 断的癫痫患者两年保留率为76．8％。其中女性患者为86．6％。高于男性患者的65％(PO．01)．20岁 及以下的男性及女性患者较20岁以上患者保留率均低。相应男性为45．o％对74．4％和女性为75．7％ 对95．2％。男性及女性患者比较差异有显著意义PO．05。结论：拉莫三嗪单药治疗新诊断的癫痫患者 韵两年保留率较高。加强对男性及青少年患者的用药管理可提高保留率，增加治疗依从性。 [关键词]拉莫三嗪；癫痫；保留率 OHtwo retentionratioof tonew Study years iamotriginemonotherapydiagnosedepilepsy patients ZHENGNaizhi，WANGMin，SHEN al Hongwei，et Medical DeptofNeurology，A|liliatedOingdaoMunicipalHospital CollegeofQingdaoUniversity。 Chirm 岱ngdao(266011)，Shandong thetwo retentionratioof tonewdi— i-Abstract]Objective：Tostudy years lamotriginemonotherapy of tWO 1 for in 38 agnosedepilepsypatients．Methods：Theapplicationlamotriginemonotherapyyears pa‘ tientswith combinedwithclinic andareturnvisit newlydiagnosedepilepsy foilow-up bytelephone．Re- tWO retentionratioof is suits：The 76．8％in tO years lamotrigine monotherapynewlydiagnosedepilepsy retentionratioof inwomen thanthatin patients．The lamotriginepatients(86．6％)washigher patients (65．O％)(PO．01)．Thetwo retentionratioOf inmaleandfemale underthe years lamotrigine patients of20 oldwaslowerthanthatin above age years patients20(45．O％vs74．4％；75．7％VS95．2％)(male andfemale PO．05)．Conclusions：Theretentionratioof isratherinmonother— patients lamotriginehigh tO retentionratioand of can spynewlydiagnosedepilepsypatients．The increasingcompliancelamotrigine beraised ofmedicineinm