2型糖尿病周围神经病变危险因素及临床指标变化.pdfVIP

JOURNAL OF J INING M EDICAL COL LEGE V ol32 No. 3 2009 175 2 型糖尿病周围神经病变危险因素及临床指标变化 孙 琳 耿厚法 班 博 ( , 272029) 目的 探讨2 型糖尿病周围神经病变的危险因素及相关临床指标的变化方法 280 名2 型糖尿 病患者根据有周围神经病变分 单纯糖尿病组及糖尿病周围神经病变组检测相关的22 个临床指标, 如病程 2 血压血糖糖化血红蛋白(HbAlc) 总胆固醇甘油三脂及 C肽等, 并对其进行t 检验 检验及Logistic 多因 素回归分析结果 2 型糖尿病并发周围神经病变组与无周围神经病变组比较有更高的微球蛋白( t = 2 2403,P 005) , 较大的年龄( t = 2 617,P 001) 及更长的病程( t = 5653, P 001) ; 微球蛋白( OR= 2 1344,P 005) 及糖尿病病程(OR= 1 135,P 001) 与周围神经病变的发生呈显著正相关结论 微球蛋 2 白及糖尿病病程是2 型糖尿病周围神经病变的危险因素 糖尿病周围神经病变; 2 型糖尿病; 危险因素 :R5872 :A : 2009) Study on the correlated risk factors and the changes of related clinical parameters about diabetic peripheral neuropathy(DPN) of type 2 diabetes(T2DM) S UN L in , GEN G H ouFa, BA N B o (Affiliated Hospital of Jining Medical Coll ege Jining Shandong 272029) Abstract:Obj ective T o inv estigate the corr elated risk factors and the changes of related clinical parameter s about diabeti c peripheral neuropathy of t ype 2 diabetes (T 2DM) . Methods 280 patients with T 2DM were random ly divi ded into gr oup1( no DPN) and gr oup 2 we detected their correlation of 22 clinical data including cour se of the disease bl ood pr essur e blood glucose gly cosy lated hemogl obin (HbAl c) total serum chol esterol triglyceride C 2 pe