低钙透析液对高钙、高磷腹膜透析患者钙磷代谢的影响.pdfVIP

·864· ·论著· 低钙透析液对高钙、高磷腹膜透析患者钙磷代谢的影响 李海坚1 黄志清1 韩小彤2 (1．广东医学院附属医院肾脏内科，广东湛江 524001； 2．湖南省人民医院血液净化中心，湖南 长沙410002) [摘要]【目的】观察在高钙、高磷的腹透患者中应用低钙透析液调节钙磷代谢的有效性。【方法】选择高 卧床腹膜透析(CAPD)治疗，观察透析开始时、3个月后、6个月后的血钙、血磷及PTH水平。【结果】治疗后3 个月，血钙、血磷均下降，与透析开始时相比有统计学意义，PTH有所上升，但无统计学意义。治疗6个月后， 血钙、血磷较透析开始时下降明显，PTH上升明显，且差异均有显著性。【结论】使用低钙透析液能够有效纠 正高钙、高磷及低PTH患者的钙磷失衡，有利于提高患者的生存质量。 [关键词]钙／代谢；磷／代谢； 腹膜透析； 透析液 of EffectLowCalcium OnSerum MetabolisminPeritoneal Dialysate Calcium—phosphate Dialysis PatientsLIHai-jian。HUANGZhi～qing。HANXiao-tong(GuangdongHospital，Guangdong Medical 524001，(_Taina) College，历n巧iang observethe oflowcalcium onserumcalciumand [Abstract][Objective]Toavailability dialysate phosphor· USmetabolismin with and peritonealdialysispatientshypercalcinemia one with and wereundertakenCAPDwithlow patientshypercalcinemia，hyperphosphatemiaPTH150pg／ml calcium andafter thelowcalcium for3and6 serumcalci— dialysate．Before months，the using dialysatetherapy 3 thelevelsofserum andintact hormoneweremeasured．[Results]Aftermonths um，phosphorusparathyroid calciumand decreased thelevelofserumPTHincreased phosphorussignificantly(PO．05)。and slightly(P 6monthsthelevelsofserumcalciumand decreased 0．05)．After phosphorussignificantl认PO．05)，and level the ofserumPTHalsoincreased calcium couldef— significantly(PO．05)．[Conclusion]Lowdialysate correcttheimbalanceofcalciumand ofthe with fectively phosphoruspatientshypercalcinemia，hyperphos— and itcouldalsocorrectthemetastaticcalcifica