复合膳食纤维对大鼠急性胰腺炎时肠粘膜屏障的保护研究.pdf

1 E×pE口工MENTAL日Tu口Y实验研究 CH工NAHEAL TH工N口UBTQY 复合膳食纤维对大鼠急性胰腺炎时肠粘膜屏障的保 护研究 张利东啦武华， 山西太原030001 fiber 【摘要1目的探讨复合膳食纤维(dietary complex，DFc)在大鼠急性胰腺炎(acute 鼠血清中内毒素、D～乳酸的变化。结果c组和D组血清内毒素和D一乳酸的释放低于A组和B组“≮o．05)．B组血清内毒素 性胰腺炎大鼠肠黏膜屏障功能有一定的保护作用。 【关键词】急性胰腺炎；大鼠；复合膳食纤维；能全素；内毒素；D一乳酸 【中图分类号】R576 【文献标识码】A 【文章编号】1672—565412014)03{c卜0022—03 ProtectiOnOf nber onratintestinalmucosaIbarrierofacute dietarycomplex pancreatitis zHANC hu叠 Liaon窖。WU 1．ShanxiMedieal ofGeneral of uniVersi吼Taiyuan 030001，China；2．DepanmentSu昭ery，thePeople’sHospitalQing】【uCounty， ofGeneral First ofShanxiMedical Qingxu03()400，China；3．DepartmentSurgery，tIle Hospital University，Taiyuan030001，China 【Abstracq0bjec6Ve’ro fiber acute mechanlsmofactionoftIIeintestinal exploredietarycomplex (AP)，s (DFC)onpancreatitis mucosal b撕er．MethodsAPratmodelwasestablishedwith5％sodiumtaumcholatewhich imo was汹eetedp孤creaticocholang ratswere diVidedintofour model Nutrition retmgradely．44randoⅡdy gmups．Simplegroup A)，Enteral B)， (group group@Dup Nutrison+compositedietaJyfiber【solubledietary dietar)r fiber(SDD：insolublefiber(ID耵=1：3】(Gmup fiber blood of dietary extlacted veinandaor