爱普列特减少经尿道前列腺汽化电切术中出血的作用研究.pdfVIP

15 4 河南医学研究 Vol . 15 No . 4 2006 12 HENAN MEDICAL RESEARCH December 2006 : 1004437X( 2006) 临床研究 李启忠, 王向阳 ( 45000 3) : 目的: 5_ ( transurethral uaporization o the prostate,TUVP) 方法: TUVP ( benign prostatic hyper plasia, BPH) 84 , 42 , ; SP ( eNOS) VEGF 结果: eNOS 315% , VEGF ( P 005) ( 42 15) ml/ g, ( 71 23) ml/ g, ( P 005) 结论: VEGF eNOS , , TUVP : ; ; : R697+ 3 : A Preoperative epristeride on decreasing operative bleeding dur ing transurethral vaporization of prostate LI Qi_zhong, WANG Xiang_yang ( Dep artment of Urology , H enan Provencial People! s H osp ital, Zhengzhou 450003 , China Abstract : Obj ective : Study the e ect o preoperative epristeride on decreasing operative bleeding dur ing transurethral vaporization o the prostate (TUVP) . Methods: 42 patients pretreaded with epristeride be ore TUVP and 42 patients without such a preoperative management, calculated the operative bleeding volume, eNOS and VEGF expression were measured by ISH SP method in prostatic tissue. Results: The expression o eNOS in epristeride group decreased 315% compared with control group, and the positive expression rate o VEGF in treated group is lower than that in control group obviously( P 005) . In epristeride group and control group the operative bleeding are( 42 15) ml/ g and( 71 23) ml/ g( P 005) . Conclusion : The VEGF and eNOS expression and angiogenesis in the prostate t issue are sup pressed, blood loss during operation(TUVP) decreased by preoperative use o epristeride. Keywords: epristeride; transurethral vaporization o the prostate ( TUVP) ; benign prostatic hyperplasia 2