黄芩解热化学成分述评_杨忻.pdfVIP

第 27 卷 第 6期 Vol. 27 No. 6 2 0 0 9 年 6 月 CH INESE ARCH IVES OF TRAD IT OI NAL CH INESE M ED CI INE Jun. 2 0 0 9 杨 忻, 孟庆刚 (, 100029) : 近几年, 我国中医药的发展备受关注, 在研究者的努力下, 中医药 业逐渐走向规范化现代化和国 际化, 在世界舞台上发挥着越来越重要的作用随着中药提取分离技术的不断完善和发展, 在国内外对黄芩的研 究中, 不断发现新的具有生物活性的化合物, 寻找黄芩新资源已经成为今后的研究方向但是, 在黄芩发挥疗效 的有效物质基础探索方面却少有进展, 尤其是在黄芩解热化学成分的研究方面, 而是把黄芩中含量较多的化学成 分) ) ) 黄芩苷作为黄芩解热的主要化学成分进行研究, 未免有失偏颇对黄芩解热化学成分的研究可以从药效 学入手, 结合指纹图谱和谱效关系, 逐步分析与解热关系最为密切的化学物质或成分配比, 再进行药效学研究, 来 说明黄芩解热的物质基础 : 黄芩; 解热; 化学成分; 物质基础 : R285. 5; R284 : A : 1673- 7717( 2009) 06- 1183- 04 R educing Fever Chem istry Com position S tudy of Scutellaria YANG X in, MENG Q ing-gang ( Be ising Un iversit of C lineseM edicin e, B eijing 100029, Ch in a) Abstrac:t In the last few ears, under the effort of Ch inesem edicine researchers, our traditional m ed icine has been more graduall, m odern ization and internationall. W ith the developm ent of the w ithdraw s and the separate techn ique of the Ch inese herbalm edicine, w e d iscovered new com pound of the living creatu re activit continuousl during the research of Scutellaria. It is a new d irection to research new resources. H owever, there is a little progress on the research ing of the living m aterial foundation w hich m akes scutellaria exertive treatm ent, especiall on the stud of solving the hot chem istr com position. On the contrar , w em ade the baicalin been them ain chem istr m aterialw hen Scu tellaria reduce fever, on l because its conten t is them ost. A s far as m concern, it is to lose one- side. W e can start from the pharm acod nam ics of the chem ical constituents of baicalin w ith spectral fingerprint and- effect relat