飞行时间质谱与四级杆质谱的对比.pdfVIP

technical note The Advantages of Time of Flight Mass Spectrometry for Elemental Analysis GBC Scientific Equipment Pty Ltd Introduction ICP-MS is a powerful technique that provides is responsible for a number of weaknesses of almost complete elemental and isotopic the technique including limited precision at analysis for a diverse range of samples. Since high speed and for a large number of the release of the first commercial ICP-MS elements, low sample throughput for full instrument in the early 1980’s, the technique mass range analysis and limited capability in has gained wide acceptance in a vast range of handling transient samples for multi-element disciplines including the analysis of analysis. environmental, biological, nuclear, geological and industrial samples. Table 1 details some of the major strengths and weakness of currently available Until now the most common commercially commercial ICP-MS instrumentation based available ICP-MS instruments have utilized on quadrupole technology. quadrupole mass analyzers. A diagram of a typical quadrupole mass analyzer is shown in Orthagonal Accelerator Ion TOF Analyser Detector Figure 1(a). DC and RF voltages are applied Packets to each pair of rods and for a given set of DC and RF voltages, ions of a particular mass to Ion Beam Flight Tube charge (m/z) ratio will have a path through the rods and strike the ion detector. For Plasma Torch multi-element analysis, the applied voltages may be changed cont