湖北地区普通人群卡波氏肉瘤相关疱疹病毒感染的血清学分析.pdfVIP

21 2 21 297-101 2006 3 VIROLOGICA SINICA March 2006 * 1** 1,2 1,2 1,2 1,2 , Shou-Jiang Gao1** 1. 430071; 2. 100039; 3. Children’s Cancer Research Institute and Departments of Pediatrics, Microbiology and Immunology, Molecular Medicine, and Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA Seroprevalence of Kaposi’s Sarcoma-associated Herpesvirus in the General Population from Hubei Province FANG Qin1**LIU Juan1,2BAI Zhi-qiang1,2 KANG Tao1,2HE Zhi-heng1,2 HU Zhi-hong1Shou-Jiang Gao1,3** (1. State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071; 2. Graduate School ,Chinese Academy of Sciences, Beijing 100039,China ; 3. Children’s Cancer Research Institute and Departments of Pediatrics, Microbiology and Immunology, Molecular Medicine, and Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA) Abstract Kaposi’s sarcoma-associated herpes-virus (KSHV), also known as Human herpesvirus 8 (HHV-8) is etiologically linked to the development of Kaposi’s sarcoma(KS), the most commonly found cancers in patients with AIDS. Extensive epidemiology studies have shown that the epidemiology of KSHV mimics that of KS displaying distinct geographic distribution patterns with low prevalence in North America and Europe, medium prevalence in Eastern European and Mediterranean regions, and