《Liquid Chromatographyelectrospray Ionization Tandem Mass Spectrometry for Simultaneous Determination of Metformin and Glimepiride in Beagle Dog Plasma and Bioequivalence Study》.pdfVIP
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CHEM.RES.CHINESEUNIVERSITIES
2012.28(3).399.~405
IonizationTandem
LiquidChromatography—electrospray
Mass forSimultaneousDeterminationof
Spectrometry
Metforminand in
GlimepirideBeagle
Dog
Plasmaand
BioequiValenceStudy
BAI Xiao.wei
Jingl”,SHI 1,DU Bai1,
Ying-fengl,XIANG
WANGShuailandCAO
De.yin91。
,.School 05001
ofPharmacy,Hebei 7,P.R.China,
Medical翰fvP坶f≯,ShUiazhuang
Fourth Medical
2.DepartmentofPharmacy,theHospitalofltebei University,
05001
7.尸.R.China
Sh口iazhuang
AbstractAsensitiveand
selective ionizationtandemmass
liquid
ehromatography-electrosprayspectrometry(LC·
usedforthesimultaneousdeterminationof in
ESI-MS/MS)was metforminand with
glimepiridebeagledogplasma
asinternal with the ISwere
glipizide standard(IS).After methanol,both and
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