《Luminescence Studies on Interaction of an Isoquinoline Alkaloid with Calf Thymus DNA in Aqueous Medium and on Solid Substrate》.pdfVIP
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CHEM.RES.CHINESEUNIVERSITmS
2012,28(4),614—619
onInteractionofan Alkaloidwith
LuminescenceStudies Isoquinoline
Calf DNAin MediumandonSolidSubstrate
ThymusAqueous
M.F.3+
LI Chuan扩andCHOIManin
Jun.fenl,SHIWen.ta02,HANXiu.yin91,DoNG
andChemicnl and
i.School西ChemistryEngineering.2.Rese倒chCem凹钌Environmem谢Science
0300D6,PJR。Clizf胛口i
E昭胁e已,f,t吕.S话以,£xf(历fve,苫由剪砀纱“口,z
B印峨st R.China
3÷Depnrtmem《Chemist唧,HongKong Un如erSi哆.HoHgKong.P
AbstractTheinteractionofcalf V胁
thymusDNA(ctDNA)withberbefinc(Ber)waSsyStcmaticallyinVestigated
in solution weak
and aIldonso“dsubstrate.The
UV.Vis,fluorescencephosphorescencespectroscopiesaqueous very
Berat525nmin solutioncanbe enhancedctDNA.TheUV-Vis
nuorescenceinlensityof aqueous greatly by spectnlm
nuorescenceofBeralonecouldbeobserved
showsthatBercouldbindwithDNAbvintercalation.Inaddition,strong
the ofnuorescence of
onfilter substrateaIldcanbe ctDNA
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