手法加穴位注射治疗膝骨性关节炎的临床的研究.pdf

5.4.3 药物作用机制 ······························20 5.5 治疗体会 ·········································23 6.结论·········································24 7.问题与展望········································24 7.1 存在问题 ········································24 7.2 展望 ········································24 参考文献 ·········································25 附录 ········································28 综述 ·········································30 致谢 ·········································39 攻读学位期间发表的学术论文目录 ·················40 作者声明 ···································41 个人简历 ·········································42 中 文 摘 要 目 的：观察手法加穴位注射治疗膝关节骨性关节炎的临床疗效， 并对其作用机理进行初步探讨。 方 法 : 将符合研究标准的膝关节骨性关节炎患者60 例，随机分 为治疗组和对照组。治疗组采用手法加穴位注射，对照组采用玻璃酸 钠关节内注射分别进行治疗，疗程均为5 周。治疗前后分别记录主要 临床症状、体征得分，进行计分。将治疗组和对照组治疗前后积分进 行对比，并用统计软件SPSS13.0 分析。 结 果：两组临床总疗效比较：总显控率治疗组为66.6% ，对照 组为 46.6% ，经统计学分析 P =0.0320.05，两组疗效比较有显著 性意义，治疗组优于对照组；总有效率治疗组93.3% ，对照组83.3%， 经统计学分析 P=0.0470.05，两组疗效比较有显著性意义，治疗组 优于对照组。轻度病情患者临床疗效：总显控率治疗组为 100%，对 照组为 71.4%，两组比较经统计学处理P 0.05，有显著性差异，治 疗组优于对照组；总有效率两组均为100%，经统计学分析P 0.05， 两组比较无差异。中度病情患者临床疗效：总控显率治疗组为62.0%， 对照组为 40.0%，经统计学分析P 0.05，两组比较比较有显著性差 异，治疗组优于对照组；总有效率治疗组为93.8%，对照组为80.0%， 经统计学处理P 0.05,两组比较有显著性差异，治疗组优于对照组。 重度病情患者临床疗效：总控显率治疗组为 20.0%，对照组33.3%， 经统计学分析P 0.05，两组比较无有显著性差异；总有效率治疗组 为 60.0%，对照组为 66.6%，经统计学处理P 0.05，两组比较无显 著性差异。 结 论：(1)手法加穴位注射是治疗膝骨性关节炎的一种有效的中 医治疗方法，对改善膝骨性关节患者临床症状有独特疗效;(2)手法加 穴位注射尤其对轻度或中度膝骨性关节炎有显著疗效;(3)手法加穴 - 1 - 位注射治疗膝骨性关节炎具有操作简单的优点，且有良好的安全性。 关键词：膝关节； 骨性关节炎；手法；穴位注射 - 2 - Manipulation and Point-injection on treatment of osteoarthritis of the knee Osteoarthritis Clinical Research ABSTRACT Objective: To study the clincal effects of The therapy of manipulation and Point-injection on the treatment of the Knee O