两色金鸡菊的化学成分与药理作用研究进展.pdfVIP

现代药物与临床 Drugs Clinic 第 29 卷 第 5 期 2014 年 5 月 ·567 · 两色金鸡菊的化学成分和药理作用研究进展 1 1 2* 1* 姜保平 ，许利嘉 ，贾晓光 ，肖培根 1. 中国医学科学院 北京协和医学院 药用植物研究所 国家教育部中草药物质基础与资源利用重点实验室，北京 100193 2. 新疆中药民族药研究所，新疆 乌鲁木齐 830002 摘 要：两色金鸡菊 Coreopsis tinctoria Nutt. 为菊科金鸡属植物，原产于北美，在我国新疆昆仑山区被发现并在当地作为茶 饮用，至今有十多年的历史。两色金鸡菊含有的化学成分主要为黄酮类、皂苷类、有机酸、鞣质、糖类、挥发油或油脂类和 酚性成分。研究表明两色金鸡菊具有降血糖、抗氧化、降血压、降血脂等药理活性，有潜在的药用价值。综述近年来两色金 鸡菊的化学成分和药理作用，为其进一步研究开发利用提供参考。 关键词：两色金鸡菊；化学成分；药理活性；研究进展 中图分类号：R282.7 文献标志码：A 文章编号：1674 - 5515(2014)05 - 0567 - 07 DOI :10.7501/j.issn.1674-5515.2014.05.027 Research progress on the chemical constituents and pharmacological activities of Coreopsis tinctoria 1 1 2 1 JIANG Bao-ping , XU Li-jia , JIA Xiao-guang , XIAO Pei-gen 1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China 2. Xinjiang Institute of Chinese Medica and Ethnodrug, Urumqi 830002, China Abstract: Coreopsis tinctoria, the plant of Coreopsis L., Compositae, was first distributed in North America, and was described in Kunlun Mountain regions, Xinjiang, China, and has been used as herbal tea for more than ten years. The main chemical constituents separated from C. tinctoria mainly consist of flavonoids, saponins, organic acids, tannins, saccharides, essential oils, and phenolic compounds. Modern pharmacological studies have demonstrated that C. tinctoria has hypoglycemic, anti-oxidative, hypotensive, hypolipidemic activities, etc., and these results indicate potential medicinal value of this material. The recent research progress on the chemical constituents and pharmacological activities of C. tinctoria