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《2016丙肝治疗(英文)-AGA》.pdf
GASTROENTEROLOGY 2006;130:225–230
American Gastroenterological Association Medical Position
Statement on the Management of Hepatitis C
epatitis C accounts for a sizable proportion of sociation, specific recommendations are based on
Hcases of chronic liver disease, liver disease relevant published information.
deaths, and cases of hepatocellular carcinoma and rep-
resents the most common indication for liver trans- Screening
plantation. Projections based on the current preva-
lence of infection and anticipated rates of progression Routine screening of all asymptomatic adults,
suggest that the morbidity and mortality, as well as who have a low prior probability of HCV infection, is
the medical care costs attributable to hepatitis C virus not recommended. Among high-risk groups (eg, in-
(HCV) infection, will escalate alarmingly during the jection drug users, persons who received a transfusion
next 2 decades. before 1992 [when donor screening for antibody to
The substantial clinical and economic impact of HCV was introduced], persons with hemophilia who
hepatitis C focuses attention on the critical need to received clotting factors before 1987, persons with
prevent and control HCV infection. Public health frequent percutaneous exposures, immigrants from
measures, changes in behavior to avoid blood-borne countries with a high prevalence of HCV infection,
infections, and screening of donated blood and organs and persons with clinical or biochemical evidence for
for HCV have reduced dramatically the freque
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