《VEGF、CD34、Ki-67和p21在翼状胬肉中的表达及意义》.pdfVIP

IntEyeSci，Vo1．14，No．7，Ju1．2014 www．ies．net．ca Tel：02982210956 Email：UO．2000@163．com 作者单位：(215300)中国江苏省昆山市第一人 民医院 眼科 ； VEGFand Ki一67 (r=0．279，P0．05)，a positive 病理科 correlationbetweenVEGFandCD34(r=0．299，P0．05)， 作者简介 ：王丽波 ，硕士，副主任医师，研究方向：眼表疾病、屈 anegativecorrelationbewt eenVEGFandp21(r=一0．267． 光手术及眼底疾病。 P0．05)：itaIso showedthattherewasnocorrelation 通讯作者：王丽波．zhoujianwanglibo@163．coin bewt eenanywtoofCD34．Ki一67andp21(P0．05)． 收稿Et期：2014—03—19 修回日期：2014—05—28 ·CONCLUSION：(1)OverexpressionOfVEGF，Ki一67， CD34 and low expression of p21 suggest thatthese Expression and significance of VEGF， markers are concerned with the development and progressionofpterygium．(2)ExpressionofVEGFand CD34．Ki-67andp21inpterygium CD34increasesalongwiththeincreaseofclinicaltypes andstages，expressionofKi-67increasesalongwiththe Lj—BoW ang ，HaiLi，Yu—ZhouW u ，YiW ang ， increase of clinicaI stages． and expression of p21 Kai—QiangWu decreasesalong with the improvementofclinicaltypes orstages；they suggest thatthese markers may play DepartmentofOphthalmology．tlle No．1People’sHospitalof importantroles ln the developmentand recurrence of Kunshan，Kunshan215300，JiangsuProvince，China；Department pterygium．(3)There is positive correlation bewteen ofPatholoyg ，theNo．1People’sHospital ofKunshan，Kunshan VEGFand Ki一67．VEGFand CD34 aswellasnegative