Effect of ultrasonic treatment on structure and antitumor activity of mycelial polysaccharides from Cordyceps gunnii》.pdfVIP

Carbohydrate Polymers 114 (2014) 12–20 Contents lists available at ScienceDirect Carbohydrate Polymers j o u r na l h o me p a g e : w w w. elsev /locate/car bpol Effect of ultrasonic treatment on structure and antitumor activity of mycelial polysaccharides from Cordyceps gunnii Zhen-Yuan Zhu a,∗ , Wei Pang a , Yuan-Yuan Li a , Xiao-Ran Ge a , Li-Jing Chen b,∗ , Xiao-Cui Liu a , Qiang Lv a , Guo-Ling Dong a , An-Jun Liu a , Yongmin Zhang c a Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Science and Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, PR China b Key Laboratory of Freshwater Fishery Germplasm Resources, Ministry of Agriculture, Shanghai Ocean University, 201306 Shanghai, PR China c Université Pierre et Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire, CNRS UMR 8232, 4 place Jussieu, 75005 Paris, France a r t i c l e i n f o a b s t r a c t Article history: Taking mycelial polysaccharides from Cordyceps gunnii (C. gunnii ) as the study subject, the effect of ultra- Received 7 January 2014 sonic power, time and concentration of polysaccharides on antitumor activity of the polysaccharides was Received in revised form 21 July 2014 investigated. The ultrasonic processing condition of the polysaccharides was optimized by using orthogo- Accepted 23 July 2014 nal test design, and determined to be 400 W, 15 min and 1 g/L. The change of structures of polysaccharides Available online 10 August 2014 before and after ultra